Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGMT | P16455 | 4/20 | 0.54 |
| ▸ | CDK1 | P06493 | 2/20 | 0.54 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.54 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.54 |
| ▸ | CDK2 | P24941 | 2/20 | 0.54 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | MPO | P05164 | 2/20 | 0.51 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.51 |
| ▸ | TPO | P07202 | 1/20 | 0.51 |
| ▸ | EPX | P11678 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16828160 | 0.85 | MGMT (0.56) | MGMTCDK1CCNB1CCNA2CDK2 | |
| SCHEMBL26977697 | 0.84 | MGMT (0.55) | MGMTCDK1CCNB1CCNA2CDK2 | |
| SCHEMBL2234851 | 0.79 | L3MBTL1 (0.56) | MGMTCDK1CCNB1CCNA2CDK2 | |
| SCHEMBL15132057 | 0.79 | MGMT (0.50) | MGMTCDK1CCNB1CCNA2CDK2 | |
| SCHEMBL15088040 | 0.79 | MGMT (0.53) | MGMTCDK1CCNB1CCNA2CDK2 | |
| SCHEMBL16852229 | 0.79 | MGMT (0.64) | MGMTCDK1CCNB1CCNA2CDK2 | |
| SCHEMBL29162739 | 0.78 | MPO (0.46) | MGMTCDK1CCNB1CCNA2CDK2 | |
| SCHEMBL15952449 | 0.76 | HRH4 (0.56) | TSHRL3MBTL1GAAMAPTRAB9A | |
| SCHEMBL16828164 | 0.75 | MGMT (0.56) | MGMTCDK1CCNB1CCNA2CDK2 | |
| SCHEMBL26660073 | 0.75 | NUDT1 (0.67) | MGMTCDK1CCNB1CCNA2CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8268849-B2 | Multifunctional Antioxidants and methods of use thereof | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 2012-09-18 | — | — | US | disclosed |
| US-20090105269-A1 | Multifunctional Compounds and Methods of Use Thereof | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2009-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105269-A1 | Multifunctional Compounds and Methods of Use Thereof | AS3MT, OAT, NCL | MGMT 85/4885CDK1 3657/4885CCNB1 1680/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.