Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB8 | P28062 | 11/20 | 0.95 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.95 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.95 |
| ▸ | HPGD | P15428 | 2/20 | 0.95 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.95 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.95 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.95 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-Mercaptobenzothiazole SCHEMBL408087 | 0.98 | PSMB8 (1.00) | PSMB8ALDH1A1KDM4EHPGDCYP3A4 | |
| 2-Mercaptobenzothiazole SCHEMBL29433968 | 0.98 | PSMB8 (1.00) | PSMB8ALDH1A1KDM4EHPGDCYP3A4 | |
| 2-Mercaptobenzothiazole SCHEMBL29729650 | 0.95 | PSMB8 (0.95) | PSMB8ALDH1A1KDM4EHPGDCYP3A4 | |
| 2-Mercaptobenzothiazole SCHEMBL8749352 | 0.95 | PSMB8 (0.95) | PSMB8ALDH1A1KDM4EHPGDCYP3A4 | |
| 2-Mercaptobenzothiazole SCHEMBL5934103 | 0.95 | PSMB8 (0.95) | PSMB8ALDH1A1KDM4EHPGDCYP3A4 | |
| 2-Mercaptobenzothiazole SCHEMBL19514730 | 0.86 | PSMB8 (0.78) | PSMB8ALDH1A1KDM4EHPGDCYP3A4 | |
| 2-Mercaptobenzothiazole SCHEMBL5933560 | 0.83 | PSMB8 (0.72) | PSMB8ALDH1A1KDM4EHPGDCYP3A4 | |
| 2-Mercaptobenzothiazole SCHEMBL10897718 | 0.79 | PSMB8 (0.66) | PSMB8ALDH1A1KDM4EHPGDCYP3A4 | |
| SCHEMBL10520003 | 0.77 | PSMB8 (0.63) | PSMB8ALDH1A1KDM4EHPGDCYP3A4 | |
| SCHEMBL4622486 | 0.73 | CMA1 (0.57) | PSMB8ALDH1A1KDM4EHPGDCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7476346-B2 | Composition inhibiting the expansion of fire, suppressing existing fire, and methods of manufacture and use thereof | FIRE JELL, INC. (US) | 2009-01-13 | — | — | US | disclosed |
| US-20070034823-A1 | Extinguishing a fire by applying an thixotropic fire fighting suspension of a pseudo-plastic high yield suspending agent and starch with a pH of 5.0-8.0; contains 99% water; clings to a surface positioned in any orientation and forms an exterior intumescent char coating upon fire contact | BULK IP, LLC | 2007-02-15 | — | — | US | disclosed |
| US-7163642-B2 | Composition inhibiting the expansion of fire, suppressing existing fire, and methods of manufacture and use thereof | BULK IP, LLC | 2007-01-16 | — | — | US | disclosed |
| WO-2006042064-A2 | COMPOSITION INHIBITING THE EXPANSION OF FIRE, SUPPRESSING EXISTING FIRE, AND METHODS OF MANUFACTURE AND USE THEREOF | HAGQUIST JAMES ALROY E (US) | 2006-04-20 | — | — | WO | disclosed |
| US-20060076531-A1 | Composition inhibiting the expansion of fire, suppressing existing fire, and methods of manufacture and use thereof | BULK IP, LLC | 2006-04-13 | — | — | US | disclosed |