2-Mercaptobenzothiazole

2-Mercaptobenzothiazole

SCHEMBL29433968

S=c1[nH]c2ccccc2s1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PSMB8 P28062 11/20 1.00
▸ ALDH1A1 P00352 7/20 1.00
▸ KDM4E B2RXH2 4/20 1.00
▸ HPGD P15428 2/20 1.00
▸ CYP3A4 P08684 2/20 1.00
▸ TDP1 Q9NUW8 2/20 1.00
▸ ALOX15 P16050 1/20 1.00
▸ CYP1A2 P05177 2/20 0.59
▸ CYP2C19 P33261 2/20 0.59
▸ GAA P10253 2/20 0.59
▸ CYP2C9 P11712 1/20 0.59
▸ KMT2A Q03164 6/20 0.55
▸ MAPT P10636 5/20 0.55
▸ MEN1 O00255 4/20 0.55
▸ GFER P55789 1/20 0.55
▸ NPSR1 Q6W5P4 1/20 0.55
▸ CRHBP P24387 1/20 0.47
▸ CRHR2 Q13324 1/20 0.47
▸ RAB9A P51151 3/20 0.46
▸ NPC1 O15118 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-Mercaptobenzothiazole SCHEMBL408087 1.00 PSMB8 (1.00) PSMB8ALDH1A1KDM4EHPGDCYP3A4
2-Mercaptobenzothiazole SCHEMBL5934103 0.98 PSMB8 (0.95) PSMB8ALDH1A1KDM4EHPGDCYP3A4
2-Mercaptobenzothiazole SCHEMBL4268289 0.98 PSMB8 (0.95) PSMB8ALDH1A1KDM4EHPGDCYP3A4
2-Mercaptobenzothiazole SCHEMBL8749352 0.98 PSMB8 (0.95) PSMB8ALDH1A1KDM4EHPGDCYP3A4
2-Mercaptobenzothiazole SCHEMBL29729650 0.98 PSMB8 (0.95) PSMB8ALDH1A1KDM4EHPGDCYP3A4
2-Mercaptobenzothiazole SCHEMBL19514730 0.88 PSMB8 (0.78) PSMB8ALDH1A1KDM4EHPGDCYP3A4
2-Mercaptobenzothiazole SCHEMBL5933560 0.85 PSMB8 (0.72) PSMB8ALDH1A1KDM4EHPGDCYP3A4
2-Mercaptobenzothiazole SCHEMBL10897718 0.81 PSMB8 (0.66) PSMB8ALDH1A1KDM4EHPGDCYP3A4
SCHEMBL10520003 0.78 PSMB8 (0.63) PSMB8ALDH1A1KDM4EHPGDCYP3A4
SCHEMBL18791144 0.74 PSMB8 (0.61) PSMB8ALDH1A1KDM4EHPGDCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260035573-A1 SEALANTS FOR INHIBITING CORROSION BOEING CO (US) 2026-02-05 — — US claimed
US-12297597-B2 Cellulose composition KEMIRA OYJ (FI) 2025-05-13 — — US claimed
CN-115947678-B Synthesis method of stable isotope 2H (D) marked 25-hydroxy vitamin D2 成都诺森医学检验有限公司 2024-01-16 — — CN claimed
EP-3247751-B1 ANTICORROSION COMPOSITION AND PROCESS FOR PREPARING AN ATICORROSION LAYER ON A SURFACE OF A SUBSTRATE USING SAID COMPOSITION SOCOMORE (FR) 2022-10-19 — — EP claimed
US-20260035573-A1 SEALANTS FOR INHIBITING CORROSION BOEING CO (US) 2026-02-05 — — US disclosed
US-12522735-B2 Polymeric agents and compositions for inhibiting corrosion THE BOEING COMPANY (US) 2026-01-13 — — US disclosed
US-12441894-B2 Compositions for inhibiting corrosion THE BOEING COMPANY (US) 2025-10-14 — — US disclosed
US-12297597-B2 Cellulose composition KEMIRA OYJ (FI) 2025-05-13 — — US disclosed
EP-4527912-A1 GREASE COMPOSITION FOR CONSTANT-VELOCITY JOINT AND CONSTANT-VELOCITY JOINT HERMETICALLY FILLED THEREWITH Kyodo Yushi Co., Ltd. (JP) 2025-03-26 — — EP disclosed
US-12163054-B2 Soluble corrosion resistant sol-gel THE BOEING COMPANY (US) 2024-12-10 — — US disclosed
WO-2024248035-A1 GREASE COMPOSITION 協同油脂株式会社 2024-12-05 — — WO disclosed
WO-2024248035-A1 GREASE COMPOSITION 協同油脂株式会社 2024-12-05 — — WO disclosed
US-20230094130-A1 POLYMERIC AGENTS AND COMPOSITIONS FOR INHIBITING CORROSION THE BOEING COMPANY 2023-03-30 — — US disclosed
WO-2023023298-A1 HALLUCINOGENIC AND NON-HALLUCINOGENIC COMPOUNDS AND METHODS OF MAKING AND USING THE SAME PSILOSTERICS, LLC (US) 2023-02-23 — — WO disclosed
US-11560483-B2 Compositions for inhibiting corrosion THE BOEING COMPANY (US) 2023-01-24 — — US disclosed
CN-115521325-A Boronic acid derivatives 首药控股(北京)股份有限公司 2022-12-27 — — CN disclosed
CN-115010915-A Nitrogen branched nine-arm polyethylene glycol derivative, preparation method and biological related substance modified by nitrogen branched nine-arm polyethylene glycol derivative 厦门赛诺邦格生物科技股份有限公司 2022-09-06 — — CN disclosed
US-20220244263-A1 METHODS FOR TREATING SMALL CELL NEUROENDOCRINE AND RELATED CANCERS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-08-04 — — US disclosed
EP-4011367-A1 COMPOUNDS FOR USE IN THE TREATMENT OF COVID-19 Dompe' Farmaceutici S.P.A. (IT) 2022-06-15 — — EP disclosed
US-11261336-B2 Process for applying a metal-organic framework-containing corrosion resistant coating to a substrate THE BOEING COMPANY (US) 2022-03-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260035573-A1 SEALANTS FOR INHIBITING CORROSION EPCAM, SFRP1, FZD7 PSMB8 1857/4885ALDH1A1 2774/4885KDM4E 175/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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