2-Mercaptobenzothiazole

2-Mercaptobenzothiazole

SCHEMBL408087

S=c1[nH]c2ccccc2s1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PSMB8 P28062 11/20 1.00
ALDH1A1 P00352 7/20 1.00
KDM4E B2RXH2 4/20 1.00
HPGD P15428 2/20 1.00
CYP3A4 P08684 2/20 1.00
TDP1 Q9NUW8 2/20 1.00
ALOX15 P16050 1/20 1.00
CYP1A2 P05177 2/20 0.59
CYP2C19 P33261 2/20 0.59
GAA P10253 2/20 0.59
CYP2C9 P11712 1/20 0.59
KMT2A Q03164 6/20 0.55
MAPT P10636 5/20 0.55
MEN1 O00255 4/20 0.55
GFER P55789 1/20 0.55
NPSR1 Q6W5P4 1/20 0.55
CRHBP P24387 1/20 0.47
CRHR2 Q13324 1/20 0.47
RAB9A P51151 3/20 0.46
NPC1 O15118 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-Mercaptobenzothiazole SCHEMBL29433968 1.00 PSMB8 (1.00) PSMB8ALDH1A1KDM4EHPGDCYP3A4
2-Mercaptobenzothiazole SCHEMBL5934103 0.98 PSMB8 (0.95) PSMB8ALDH1A1KDM4EHPGDCYP3A4
2-Mercaptobenzothiazole SCHEMBL8749352 0.98 PSMB8 (0.95) PSMB8ALDH1A1KDM4EHPGDCYP3A4
2-Mercaptobenzothiazole SCHEMBL4268289 0.98 PSMB8 (0.95) PSMB8ALDH1A1KDM4EHPGDCYP3A4
2-Mercaptobenzothiazole SCHEMBL29729650 0.98 PSMB8 (0.95) PSMB8ALDH1A1KDM4EHPGDCYP3A4
2-Mercaptobenzothiazole SCHEMBL19514730 0.88 PSMB8 (0.78) PSMB8ALDH1A1KDM4EHPGDCYP3A4
2-Mercaptobenzothiazole SCHEMBL5933560 0.85 PSMB8 (0.72) PSMB8ALDH1A1KDM4EHPGDCYP3A4
2-Mercaptobenzothiazole SCHEMBL10897718 0.81 PSMB8 (0.66) PSMB8ALDH1A1KDM4EHPGDCYP3A4
SCHEMBL10520003 0.78 PSMB8 (0.63) PSMB8ALDH1A1KDM4EHPGDCYP3A4
SCHEMBL11110131 0.74 PSMB8 (0.61) PSMB8ALDH1A1KDM4EHPGDCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1872 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122013274-A Direct copper electroplating process without silver paste priming 三合镁(深圳)科技有限公司 2026-05-12 CN claimed
EP-4722321-A1 GREASE COMPOSITION KYODO YUSHI CO., LTD. (JP) 2026-04-08 EP claimed
US-20260035573-A1 SEALANTS FOR INHIBITING CORROSION BOEING CO (US) 2026-02-05 US claimed
US-20250354080-A1 GREASE COMPOSITION FOR CONSTANT-VELOCITY JOINT AND CONSTANT-VELOCITY JOINT FILLED THEREWITH KYODO YUSHI CO., LTD (JP) 2025-11-20 US claimed
CN-120161034-A Surface Enhanced Raman Scattering (SERS) method for dandelion propagation inspired by 西安电子科技大学 2025-06-17 CN claimed
CN-120085008-A Kit for simultaneously detecting specific membrane protein marker and membrane protein dimer and application thereof 南京邮电大学 2025-06-03 CN claimed
EP-4527912-A1 GREASE COMPOSITION FOR CONSTANT-VELOCITY JOINT AND CONSTANT-VELOCITY JOINT HERMETICALLY FILLED THEREWITH Kyodo Yushi Co., Ltd. (JP) 2025-03-26 EP claimed
CN-119320967-A Electrolytic copper foil additive and preparation process of high-tensile warp-free 6 mu m double-electrolytic copper foil 陕西未来尖端材料科技有限公司 2025-01-17 CN claimed
CN-119192699-A Latex composite resin composition for 3D printing and preparation method and application thereof 中国科学院福建物质结构研究所 2024-12-27 CN claimed
CN-119137249-A Grease composition for constant velocity joints and constant velocity joint sealed with the same 协同油脂株式会社 2024-12-13 CN claimed
EP-0068807-B1 ACID COPPER ELECTROPLATING BATHS CONTAINING BRIGHTENING AND LEVELLING ADDITIVES M & T CHEMICALS, INC. (US) 1987-04-01 EP claimed
US-4551419-A HIGH PHOTSENSITIVITY AND CONTRAST BY INCLUDING A SULFUR COMPOUND AND A MERCAPTO-CONTAINING AZAINDENE STABILIZER FUJI PHOTO FILM CO., LTD. (JP) 1985-11-05 US claimed
EP-0152574-A1 6-Ethoxy-4-methyl-benzothiazol-2(3H)-one, processes for its preparation and medicaments containing this compound Dr. Karl Thomae GmbH (DE) 1985-08-28 EP claimed
US-4376685-A ALKYLATED EPIHALOHYDRIN-MODIFIED POLYALKYLENIMINES M&T CHEMICALS INC. (US) 1983-03-15 US claimed
EP-0068807-A2 Acid copper electroplating baths containing brightening and levelling additives M & T CHEMICALS, INC. (US) 1983-01-05 EP claimed
EP-0039818-A1 Substituted 2-(3H)-benzothiazolones, processes for their preparation, their utilization in the preparation of medicines and medicines containing them Dr. Karl Thomae GmbH (DE) 1981-11-18 EP claimed
US-4216284-A NONDIFFUSIBLE SILVER BLEACH INHIBITOR FUJI PHOTO FILM CO., LTD. (JP) 1980-08-05 US claimed
US-4119588-A Reversion resistant rubber compositions with thio carbamyl sulfenamides THE B. F. GOODRICH COMPANY (US) 1978-10-10 US claimed
US-4043942-A Modified nickel catalyst systems and their use in reductive alkylation reactions THE GOODYEAR TIRE & RUBBER COMPANY (US) 1977-08-23 US claimed
US-4001020-A DEVELOPING A SILVER HA1IDE EMULSION IN CONTACT WITH A HETEROCYCLIC THIONE AND A POLYALKYLENE OXIDE FUJI PHOTO FILM CO., LTD. (JA) 1977-01-04 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260035573-A1 SEALANTS FOR INHIBITING CORROSION EPCAM, SFRP1, FZD7 PSMB8 1857/4885ALDH1A1 2774/4885KDM4E 175/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.