2-Mercaptobenzothiazole

2-Mercaptobenzothiazole

SCHEMBL8749352

S=c1[nH]c2ccccc2s1.[Zn]

nearest known ligand 0.95

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PSMB8 P28062 11/20 0.95
ALDH1A1 P00352 7/20 0.95
KDM4E B2RXH2 4/20 0.95
HPGD P15428 2/20 0.95
CYP3A4 P08684 2/20 0.95
TDP1 Q9NUW8 2/20 0.95
ALOX15 P16050 1/20 0.95
CYP1A2 P05177 2/20 0.57
CYP2C19 P33261 2/20 0.57
GAA P10253 2/20 0.57
CYP2C9 P11712 1/20 0.57
KMT2A Q03164 6/20 0.53
MAPT P10636 5/20 0.53
MEN1 O00255 4/20 0.53
GFER P55789 1/20 0.53
NPSR1 Q6W5P4 1/20 0.53
CRHBP P24387 1/20 0.46
CRHR2 Q13324 1/20 0.46
RAB9A P51151 3/20 0.45
NPC1 O15118 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-Mercaptobenzothiazole SCHEMBL408087 0.98 PSMB8 (1.00) PSMB8ALDH1A1KDM4EHPGDCYP3A4
2-Mercaptobenzothiazole SCHEMBL29433968 0.98 PSMB8 (1.00) PSMB8ALDH1A1KDM4EHPGDCYP3A4
2-Mercaptobenzothiazole SCHEMBL5934103 0.95 PSMB8 (0.95) PSMB8ALDH1A1KDM4EHPGDCYP3A4
2-Mercaptobenzothiazole SCHEMBL4268289 0.95 PSMB8 (0.95) PSMB8ALDH1A1KDM4EHPGDCYP3A4
2-Mercaptobenzothiazole SCHEMBL29729650 0.95 PSMB8 (0.95) PSMB8ALDH1A1KDM4EHPGDCYP3A4
2-Mercaptobenzothiazole SCHEMBL19514730 0.86 PSMB8 (0.78) PSMB8ALDH1A1KDM4EHPGDCYP3A4
2-Mercaptobenzothiazole SCHEMBL5933560 0.83 PSMB8 (0.72) PSMB8ALDH1A1KDM4EHPGDCYP3A4
2-Mercaptobenzothiazole SCHEMBL10897718 0.79 PSMB8 (0.66) PSMB8ALDH1A1KDM4EHPGDCYP3A4
SCHEMBL10520003 0.77 PSMB8 (0.63) PSMB8ALDH1A1KDM4EHPGDCYP3A4
SCHEMBL11110131 0.72 PSMB8 (0.61) PSMB8ALDH1A1KDM4EHPGDCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5024773-A Methods for preparing, group II metal overbased sulfurized alkylphenols CHEVRON RESEARCH COMPANY (US) 1991-06-18 US claimed
US-4971710-A LUBRICANT ADDITIVES CHEVRON RESEARCH COMPANY (US) 1990-11-20 US claimed
US-4744921-A SULFURIZATION CATALYSTS CHEVRON RESEARCH COMPANY (US) 1988-05-17 US claimed
EP-0259974-B2 Overbased sulfurized alkyl-phenols as lubricating oil additives CHEVRON RES & TECH (US) 1997-03-26 EP disclosed
US-5024773-A Methods for preparing, group II metal overbased sulfurized alkylphenols CHEVRON RESEARCH COMPANY (US) 1991-06-18 US disclosed
US-4971710-A LUBRICANT ADDITIVES CHEVRON RESEARCH COMPANY (US) 1990-11-20 US disclosed
US-4744921-A SULFURIZATION CATALYSTS CHEVRON RESEARCH COMPANY (US) 1988-05-17 US disclosed
EP-0259974-A2 Overbased sulfurized alkyl-phenols as lubricating oil additives CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) 1988-03-16 EP disclosed