Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB8 | P28062 | 11/20 | 0.95 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.95 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.95 |
| ▸ | HPGD | P15428 | 2/20 | 0.95 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.95 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.95 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.95 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-Mercaptobenzothiazole SCHEMBL29433968 | 0.98 | PSMB8 (1.00) | PSMB8ALDH1A1KDM4EHPGDCYP3A4 | |
| 2-Mercaptobenzothiazole SCHEMBL408087 | 0.98 | PSMB8 (1.00) | PSMB8ALDH1A1KDM4EHPGDCYP3A4 | |
| 2-Mercaptobenzothiazole SCHEMBL8749352 | 0.95 | PSMB8 (0.95) | PSMB8ALDH1A1KDM4EHPGDCYP3A4 | |
| 2-Mercaptobenzothiazole SCHEMBL4268289 | 0.95 | PSMB8 (0.95) | PSMB8ALDH1A1KDM4EHPGDCYP3A4 | |
| 2-Mercaptobenzothiazole SCHEMBL29729650 | 0.95 | PSMB8 (0.95) | PSMB8ALDH1A1KDM4EHPGDCYP3A4 | |
| 2-Mercaptobenzothiazole SCHEMBL19514730 | 0.86 | PSMB8 (0.78) | PSMB8ALDH1A1KDM4EHPGDCYP3A4 | |
| 2-Mercaptobenzothiazole SCHEMBL5933560 | 0.83 | PSMB8 (0.72) | PSMB8ALDH1A1KDM4EHPGDCYP3A4 | |
| 2-Mercaptobenzothiazole SCHEMBL10897718 | 0.79 | PSMB8 (0.66) | PSMB8ALDH1A1KDM4EHPGDCYP3A4 | |
| SCHEMBL10520003 | 0.77 | PSMB8 (0.63) | PSMB8ALDH1A1KDM4EHPGDCYP3A4 | |
| SCHEMBL18791144 | 0.72 | PSMB8 (0.61) | PSMB8ALDH1A1KDM4EHPGDCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060276339-A1 | Methods and compositions for increasing the efficacy of biologically-active ingredients | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2006-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060276339-A1 | Methods and compositions for increasing the efficacy of biologically-active ingredients | ENPP1, ENPP3, SMPD1 | PSMB8 3746/4885ALDH1A1 2504/4885KDM4E 1139/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.