Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.48 |
| ▸ | GSK3B | P49841 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.46 |
| ▸ | WNT3A | P56704 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NFATC1 | O95644 | 2/20 | 0.44 |
| ▸ | HAT1 | O14929 | 2/20 | 0.43 |
| ▸ | EP300 | Q09472 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30066929 | 0.88 | GPR84 (0.51) | GPR84CYP2C19TP53SMN1; SMN2NPSR1 | |
| SCHEMBL2971915 | 0.85 | TP53 (0.47) | GPR84CYP2D6CYP2C9CYP2C19TP53 | |
| SCHEMBL30101234 | 0.84 | DYRK1A (0.51) | GPR84CYP2D6CYP2C9CYP2C19DYRK1A | |
| SCHEMBL2052704 | 0.84 | DYRK1A (0.51) | GPR84CYP2D6CYP2C9CYP2C19DYRK1A | |
| SCHEMBL13660647 | 0.82 | DYRK1A (0.48) | GPR84CYP2D6CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL700094 | 0.81 | GPR84 (0.63) | GPR84TP53SMN1; SMN2NPSR1DYRK1A | |
| SCHEMBL3279652 | 0.80 | GPR84 (0.79) | GPR84TP53SMN1; SMN2NPSR1MEN1 | |
| SCHEMBL29988308 | 0.80 | GPR84 (0.79) | GPR84TP53SMN1; SMN2NPSR1MEN1 | |
| SCHEMBL2628950 | 0.80 | CYP2D6 (0.48) | GPR84CYP2D6CYP2C9CYP2C19DYRK1A | |
| SCHEMBL15753598 | 0.78 | GSK3B (0.48) | GPR84CYP2D6CYP2C9CYP2C19DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7608627-B2 | I kappa B kinase inhibition; diabetes; (7-Chloro-1H-pyrrolo[2,3-c]pyridin-2-yl)methanol; N-Benzyl-7-chloro-1H-pyrrolo[2,3-c]pyridine-2-carboxamide | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-10-27 | — | — | US | disclosed |
| US-20080064715-A1 | 6-Azaindole Compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-03-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080064715-A1 | 6-Azaindole Compound | RELA, NFKBIA, GPR119 | GPR84 1480/4885CYP2D6 2213/4885CYP2C9 1914/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.