Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 3/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.36 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.36 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | MIF | P14174 | 4/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29615759 | 1.00 | CES1 (0.47) | CES1TDP1L3MBTL1MAOBCYP2A6 | |
| SCHEMBL13936139 | 0.81 | CES1 (0.42) | CES1TDP1L3MBTL1MAOBCYP2A6 | |
| SCHEMBL30856147 | 0.78 | TDP1 (0.49) | TDP1L3MBTL1MAOBMAOAPARP1 | |
| SCHEMBL8885671 | 0.77 | CES1 (0.47) | CES1TDP1L3MBTL1MAOBCYP2A6 | |
| SCHEMBL2063760 | 0.77 | ESR1 (0.54) | CES1TDP1L3MBTL1MAOBCYP2A6 | |
| SCHEMBL29952458 | 0.77 | ESR1 (0.54) | CES1TDP1L3MBTL1MAOBCYP2A6 | |
| SCHEMBL4268093 | 0.76 | MITF (0.48) | CES1TDP1L3MBTL1MAOBSRD5A1 | |
| SCHEMBL3267426 | 0.75 | F7 (0.42) | TDP1L3MBTL1MAOBPARP1PARP10 | |
| SCHEMBL31620343 | 0.75 | PARP1 (0.42) | TDP1L3MBTL1PARP1PARP10SRD5A1 | |
| SCHEMBL3267757 | 0.75 | PARP1 (0.42) | TDP1L3MBTL1PARP1PARP10SRD5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022123336-A1 | CHROMENO [4,3-B] QUINOLINE COMPOUNDS AND THEIR SYNTHESIS BY USING SILICOTUNGSTIC ACID [H4SIW12O40] | HEGDE SUBRAMANYA GOPAL (IN) | 2022-06-16 | — | — | WO | disclosed |
| CN-111440162-A | Thiazole dihydronaphthalene derivative and application thereof in metabolic diseases | 邱曲真 | 2020-07-24 | — | — | CN | disclosed |
| WO-2013041807-A1 | NEW TRICYCLIC COMPOUNDS, PREPARATION METHOD AND USE THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2013-03-28 | — | — | WO | disclosed |
| WO-2009110002-A1 | NOVEL EFFLUX PUMP INHIBITORS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2009-09-11 | — | — | WO | disclosed |
| US-20090036492-A1 | Novel Cercosporamide Derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2009-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090036492-A1 | Novel Cercosporamide Derivative | GPR119, CBR3, SLC5A2 | CES1 28/4885TDP1 4587/4885L3MBTL1 863/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.