Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MITF | O75030 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | TNKS | O95271 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methylpiperazine SCHEMBL4565823 | 0.87 | MAPK1 (0.47) | MITFHSP90AA1RAB9AHDAC3TNKS | |
| Methylpiperazine SCHEMBL4551422 | 0.87 | MAPK1 (0.47) | MITFHSP90AA1RAB9AHDAC3TNKS | |
| SCHEMBL4551139 | 0.81 | ESR1 (0.50) | MITFHSP90AA1RAB9AHDAC3TNKS | |
| SCHEMBL4264174 | 0.81 | ESR1 (0.50) | MITFHSP90AA1RAB9AHDAC3TNKS | |
| SCHEMBL4266901 | 0.81 | RAB9A (0.48) | MITFHSP90AA1RAB9AHDAC3TNKS | |
| SCHEMBL4419566 | 0.80 | CES1 (0.37) | MITFHSP90AA1RAB9AMEN1MAPT | |
| SCHEMBL4270390 | 0.80 | MEN1 (0.47) | RAB9AMEN1MAPTMAPK1KMT2A | |
| SCHEMBL4278133 | 0.80 | L3MBTL1 (0.51) | MITFHSP90AA1RAB9AKDM4EALDH1A1 | |
| SCHEMBL4273945 | 0.77 | MITF (0.47) | MITFHSP90AA1RAB9AHDAC3TNKS | |
| SCHEMBL4270374 | 0.77 | MITF (0.47) | MITFHSP90AA1RAB9AHDAC3TNKS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009110002-A1 | NOVEL EFFLUX PUMP INHIBITORS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2009-09-11 | — | — | WO | claimed |
| WO-2009110002-A1 | NOVEL EFFLUX PUMP INHIBITORS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2009-09-11 | — | — | WO | disclosed |