Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 15/20 | 0.66 |
| ▸ | MMP9 | P14780 | 11/20 | 0.66 |
| ▸ | ADAMTS4 | O75173 | 3/20 | 0.66 |
| ▸ | MMP13 | P45452 | 2/20 | 0.61 |
| ▸ | MMP14 | P50281 | 2/20 | 0.61 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.60 |
| ▸ | MMP1 | P03956 | 1/20 | 0.60 |
| ▸ | MMP3 | P08254 | 1/20 | 0.60 |
| ▸ | MMP7 | P09237 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | MMP8 | P22894 | 1/20 | 0.49 |
| ▸ | MMP12 | P39900 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5047244 | 0.86 | MMP2 (0.53) | MMP2MMP9ADAMTS4MMP13MMP14 | |
| SCHEMBL4262393 | 0.85 | MMP13 (0.47) | MMP2MMP9ADAMTS4MMP13MMP14 | |
| SCHEMBL5037885 | 0.84 | MMP2 (0.52) | MMP2MMP9ADAMTS4MMP13MMP14 | |
| SCHEMBL5037883 | 0.84 | MMP2 (0.52) | MMP2MMP9ADAMTS4MMP13MMP14 | |
| SCHEMBL5037617 | 0.84 | MMP2 (0.53) | MMP2MMP9ADAMTS4MMP13MMP14 | |
| SCHEMBL5037620 | 0.84 | MMP2 (0.53) | MMP2MMP9ADAMTS4MMP13MMP14 | |
| SCHEMBL6545297 | 0.81 | MMP2 (1.00) | MMP2MMP9ADAMTS4MMP13MMP14 | |
| SCHEMBL1920507 | 0.81 | MMP2 (1.00) | MMP2MMP9ADAMTS4MMP13MMP14 | |
| SCHEMBL32691761 | 0.81 | MMP2 (1.00) | MMP2MMP9ADAMTS4MMP13MMP14 | |
| SCHEMBL4271261 | 0.80 | MMP2 (0.66) | MMP2MMP9ADAMTS4MMP13MMP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090082392-A1 | Substituted Carboxylic Acids | THE INSTITUTES FOR PHARMACEUTICAL DISCOVERY LLC | 2009-03-26 | — | — | US | claimed |
| JP-2006525329-A | — | — | 2006-11-09 | — | — | JP | claimed |
| EP-1620420-A2 | SUBSTITUTED CARBOXYLIC ACIDS | The Institutes for Pharmaceutical Discovery, LLC (US) | 2006-02-01 | — | — | EP | claimed |
| US-20040266788-A1 | Substituted carboxylic acids | THE INSTITUTE FOR PHARMACEUTICAL DISCOVERY LLC | 2004-12-30 | — | — | US | claimed |
| WO-2004099168-A2 | SUBSTITUTED CARBOXYLIC ACIDS | THE INSTITUTES FOR PHARMACEUTICAL DISCOVERY, LLC (US) | 2004-11-18 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040266788-A1 | Substituted carboxylic acids | PTP4A1, PTPRS, G6PC1 | MMP2 3873/4885MMP9 4496/4885ADAMTS4 4593/4885 |
| US-20090082392-A1 | Substituted Carboxylic Acids | PTPRJ, PTPRS, PTPRG | MMP2 3614/4885MMP9 4346/4885ADAMTS4 4500/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.