Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UBE2M | P61081 | 2/20 | 0.42 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | PTGIR | P43119 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4270761 | 1.00 | UBE2M (0.42) | UBE2MDCUN1D1PGRALDH1A1S1PR1 | |
| SCHEMBL4268261 | 0.99 | UBE2M (0.43) | UBE2MDCUN1D1PGRALDH1A1S1PR1 | |
| SCHEMBL4268265 | 0.99 | UBE2M (0.43) | UBE2MDCUN1D1PGRALDH1A1S1PR1 | |
| SCHEMBL13657696 | 0.89 | UBE2M (0.41) | UBE2MDCUN1D1PGRALDH1A1S1PR1 | |
| Lithium Ion SCHEMBL4270763 | 0.88 | UBE2M (0.41) | UBE2MDCUN1D1PGRALDH1A1S1PR1 | |
| SCHEMBL4272537 | 0.87 | UBE2M (0.42) | UBE2MDCUN1D1PGRALDH1A1S1PR1 | |
| SCHEMBL4272601 | 0.87 | UBE2M (0.42) | UBE2MDCUN1D1PGRALDH1A1S1PR1 | |
| SCHEMBL4276761 | 0.87 | MEN1 (0.49) | ALDH1A1S1PR1KDM4EMEN1KMT2A | |
| SCHEMBL4276753 | 0.87 | MEN1 (0.49) | ALDH1A1S1PR1KDM4EMEN1KMT2A | |
| SCHEMBL4268251 | 0.85 | MEN1 (0.50) | ALDH1A1S1PR1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7608739-B2 | Mitotic kinesin inhibitors | MERCK & CO. INC. (US) | 2009-10-27 | — | — | US | disclosed |
| US-20080234281-A1 | Mitotic Kinesin Inhibitors | MERCK SHARP & DOHME CORP. | 2008-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080234281-A1 | Mitotic Kinesin Inhibitors | KIF5B, KIF2C, KIF18B | UBE2M 2628/4885DCUN1D1 1388/4885PGR 3979/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.