Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | NCF1 | P14598 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 2/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.48 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL6630123 | 0.98 | LOXL2 (0.60) | LOXL2CYP1A2NCF1KDM4EALDH1A1 | |
| SCHEMBL996284 | 0.98 | LOXL2 (0.64) | LOXL2CYP1A2NCF1KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL2887499 | 0.96 | LOXL2 (0.62) | LOXL2CYP1A2NCF1KDM4EALDH1A1 | |
| SCHEMBL6629717 | 0.83 | MAPT (0.54) | LOXL2NCF1KDM4EALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL11972049 | 0.82 | MAPT (0.52) | LOXL2NCF1KDM4EALDH1A1LMNA | |
| SCHEMBL7747842 | 0.82 | LOXL2 (0.60) | LOXL2CYP1A2NCF1KDM4EALDH1A1 | |
| SCHEMBL7599320 | 0.80 | LOXL2 (0.58) | LOXL2CYP1A2NCF1KDM4EALDH1A1 | |
| Benzene SCHEMBL6631416 | 0.79 | LOXL2 (0.62) | LOXL2CYP1A2NCF1KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL28182640 | 0.79 | LOXL2 (0.56) | LOXL2CYP1A2NCF1KDM4EALDH1A1 | |
| SCHEMBL31599195 | 0.78 | LOXL2 (0.67) | LOXL2CYP1A2NCF1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090239890-A1 | SPIRO SUBSTITUTED CYCLOPROPANE COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS | SCHERING CORPORATION | 2009-09-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090239890-A1 | SPIRO SUBSTITUTED CYCLOPROPANE COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS | ADAMTS1, ADAMTS13, ADAMTS7 | LOXL2 1248/4885CYP1A2 1093/4885NCF1 942/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.