SCHEMBL4275002

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4639466	0.91	TPH1 (0.36)	RXFP1NFE2L2KDM4EPPARGPPARA
	SCHEMBL4273666	0.89	LCLAT1 (0.34)	RXFP1NFE2L2KDM4EPPARGPPARA
	SCHEMBL20780191	0.89	LCLAT1 (0.34)	RXFP1NFE2L2KDM4EPPARGPPARA
	SCHEMBL4276646	0.84	PPARG (0.38)	NFE2L2KDM4EPPARGPPARANPSR1
	SCHEMBL4269836	0.84	GSK3B (0.40)	KDM4EKMT2AALDH1A1MAPTMEN1
	SCHEMBL4277053	0.84	LCLAT1 (0.36)	NFE2L2KDM4EPPARGPPARANPSR1
	SCHEMBL4275001	0.80	KDM4E (0.39)	RXFP1KDM4EPPARGPPARANPSR1
	SCHEMBL4286018	0.80	PPARG (0.37)	KDM4EPPARGPPARANPSR1LCLAT1
	SCHEMBL20780184	0.79	SMN1; SMN2 (0.38)	KDM4ENPSR1LCLAT1KMT2AALDH1A1
	SCHEMBL4280811	0.79	LMNA (0.40)	KDM4EKMT2AMAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.