SCHEMBL4275124

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4280597	0.87	ALDH1A1 (0.52)	ALDH1A1LMNAGAAMAPTMAPK1
	SCHEMBL4284039	0.86	CHRM2 (0.51)	KCNH2CACNA1IHTR4CACNA1HCYP2D6
	SCHEMBL1430776	0.84	KCNH2 (0.67)	KCNH2CACNA1IHTR4CACNA1HCYP2D6
	SCHEMBL20056161	0.84	ALDH1A1 (0.58)	ALDH1A1LMNAGAAMAPTMAPK1
	SCHEMBL4279835	0.83	KCNH2 (0.49)	KCNH2CACNA1IHTR4CACNA1HCYP2D6
	SCHEMBL4278158	0.83	KCNH2 (0.55)	ALDH1A1KCNH2CACNA1IHTR4
	SCHEMBL4284048	0.82	CACNA1I (0.51)	KCNH2CACNA1IHTR4CACNA1HCYP2D6
	SCHEMBL4276491	0.82	CACNA1I (0.64)	KCNH2CACNA1ICACNA1HCYP2D6
	SCHEMBL4276941	0.82	CACNA1I (0.49)	KCNH2CACNA1IHTR4CACNA1HCYP2D6
	SCHEMBL19112716	0.82	ALDH1A1 (0.51)	ALDH1A1LMNAGAAMAPTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.