SCHEMBL4284039

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4279464	0.89	KCNH2 (0.49)	CHRM4GSK3BKCNH2HTR4CACNA1I
	SCHEMBL4277358	0.89	CHRM2 (0.52)	CHRM2CHRM1CXCR3EPHX2CHRM4
	SCHEMBL4272776	0.88	EPHX2 (0.52)	CHRM2CHRM1CXCR3EPHX2CHRM4
	SCHEMBL4275124	0.86	ALDH1A1 (0.51)	KCNH2HTR4CACNA1ICACNA1HCYP2D6
	SCHEMBL19113313	0.86	CARM1 (0.56)	CHRM2CHRM1CXCR3EPHX2CHRM4
	SCHEMBL19112914	0.84	EPHX2 (0.50)	CHRM2CHRM1CXCR3EPHX2CHRM4
	SCHEMBL20056282	0.83	CHRM2 (0.55)	CHRM2CHRM1CXCR3EPHX2CHRM4
	SCHEMBL1430776	0.83	KCNH2 (0.67)	KCNH2HTR4CACNA1ICACNA1HCYP2D6
	SCHEMBL19113186	0.82	CHRM2 (0.55)	CHRM2CHRM1CXCR3EPHX2CHRM4
	SCHEMBL4276834	0.82	KCNH2 (0.52)	GSK3BKCNH2HTR4CACNA1ICACNA1H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.