Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 3/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LPAR3 | Q9UBY5 | 6/20 | 0.37 |
| ▸ | LPAR2 | Q9HBW0 | 5/20 | 0.37 |
| ▸ | CA1 | P00915 | 5/20 | 0.37 |
| ▸ | CA2 | P00918 | 5/20 | 0.37 |
| ▸ | CA9 | Q16790 | 5/20 | 0.37 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA3 | P07451 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8432806 | 1.00 | DNM1 (0.40) | DNM1THRBTSHRMEN1HTT | |
| SCHEMBL4275670 | 1.00 | DNM1 (0.40) | DNM1THRBTSHRMEN1HTT | |
| SCHEMBL4280436 | 1.00 | DNM1 (0.40) | DNM1THRBTSHRMEN1HTT | |
| SCHEMBL4271908 | 1.00 | DNM1 (0.40) | DNM1THRBTSHRMEN1HTT | |
| SCHEMBL1817034 | 1.00 | DNM1 (0.40) | DNM1THRBTSHRMEN1HTT | |
| SCHEMBL10384073 | 1.00 | DNM1 (0.40) | DNM1THRBTSHRMEN1HTT | |
| SCHEMBL11520008 | 0.93 | DNM1 (0.36) | DNM1THRBTSHRMEN1HTT | |
| SCHEMBL9124092 | 0.90 | ADRB2 (0.39) | DNM1THRBTSHRALDH1A1CA1 | |
| SCHEMBL927971 | 0.84 | LMNA (0.44) | THRBTSHRMEN1HTTKMT2A | |
| SCHEMBL926386 | 0.84 | LMNA (0.44) | THRBTSHRMEN1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090042749-A1 | N,N-Dialkylpolyhydroxyalkylamines | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2009-02-12 | — | — | US | disclosed |
| EP-1676831-B1 | N,N-dialkylpolyhydroxyalkylamines | AIR PROD & CHEM (US) | 2008-10-08 | — | — | EP | disclosed |
| EP-1676831-A1 | N,N-dialkylpolyhydroxyalkylamines | Air Products and Chemicals, Inc. (US) | 2006-07-05 | — | — | EP | disclosed |
| US-20060100127-A1 | N,N-dialkylpolyhydroxyalkylamines | AIR PRODUCTS AND CHEMICALS, INC. | 2006-05-11 | — | — | US | disclosed |
| EP-1637038-A2 | N,N'-dialkyl derivatives of polyhydroxyalkyl alkylenediamines | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2006-03-22 | — | — | EP | disclosed |
| US-20060013780-A1 | N,N'-dialkyl derivatives of polyhydroxyalkyl alkylenediamines | AIR PRODUCTS AND CHEMICALS, INC. | 2006-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060013780-A1 | N,N'-dialkyl derivatives of polyhydroxyalkyl alkylenediamines | AGL, SFN, MGAT1 | DNM1 3150/4885THRB 4473/4885TSHR 2728/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.