SCHEMBL4276429

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4273339	0.83	ACHE (0.50)	ACHEALDH1A1MAPTRAB9AGAA
	SCHEMBL7038180	0.78	PARP1 (0.33)	ACHEALDH1A1MAPTRAB9AGAA
	SCHEMBL35643	0.78	ELANE (0.33)	ALDH1A1MAPTRAB9AKMT2AADRA1A
	SCHEMBL17334525	0.78	GRM2 (0.33)	ACHENQO2LMNAPDPK1
	SCHEMBL2438399	0.76	ALDH1A1 (0.50)	ALDH1A1MAPTRAB9ANPSR1TSHR
	SCHEMBL7042564	0.75	NQO2 (0.50)	ALDH1A1MAPTRAB9AKMT2AADRA1A
	SCHEMBL276921	0.71	ACHE (0.56)	ACHEALDH1A1MAPTRAB9AGAA
	SCHEMBL11206718	0.71	ACHE (0.61)	ACHEALDH1A1MAPTRAB9AGAA
	SCHEMBL1973	0.70	MAPT (0.36)	ACHEALDH1A1MAPTGAATSHR
	SCHEMBL8510518	0.70	ACHE (0.54)	ACHEALDH1A1MAPTRAB9AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.