Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 3/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.34 |
| ▸ | NPY1R | P25929 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4274132 | 0.88 | MC4R (0.37) | DRD3HTR1AHTR2ATSHRNPY1R | |
| SCHEMBL4287232 | 0.83 | SLC6A3 (0.39) | HIF1ACYP2C9TSHRCYP2D6SMN1; SMN2 | |
| SCHEMBL4279426 | 0.79 | OPRL1 (0.39) | DRD3HTR1AHTR2AOPRM1OPRK1 | |
| SCHEMBL707969 | 0.73 | CCR5 (0.35) | CYP2D6ALDH1A1NPY1RKCNH2 | |
| SCHEMBL3446634 | 0.72 | MEN1 (0.34) | CYP2D6SMN1; SMN2ALDH1A1NPY1RKCNH2 | |
| SCHEMBL4554297 | 0.72 | CHRM1 (0.35) | DRD3HTR1AHTR2ACYP2D6ALDH1A1 | |
| SCHEMBL4444921 | 0.72 | CCR5 (0.34) | TSHRCYP2D6ALDH1A1CYP3A4NPY1R | |
| SCHEMBL707959 | 0.72 | CCR5 (0.37) | DRD3HTR1AHTR2AALDH1A1HTR2C | |
| SCHEMBL4444561 | 0.71 | CCR5 (0.34) | TSHRCYP2D6ALDH1A1MAPK1CYP3A4 | |
| SCHEMBL4280544 | 0.71 | SLC6A3 (0.43) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090253669-A1 | Substituted Sulfonamide Compounds | GRUENENTHAL GMBH (DE) | 2009-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090253669-A1 | Substituted Sulfonamide Compounds | SULT2A1, STS, SULT1A1 | DRD3 3341/4885HTR1A 2108/4885HTR2A 2048/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.