Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.33 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.32 |
| ▸ | CDC7 | O00311 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GSK3A | P49840 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
| ▸ | F10 | P00742 | 1/20 | 0.30 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16719968 | 0.82 | FGFR1 (0.40) | MEN1KMT2AROCK2PIM1PIM3 | |
| SCHEMBL16719992 | 0.82 | HPGDS (0.36) | MGLLKMT2AROCK2PIM1PIM3 | |
| SCHEMBL16720096 | 0.82 | MAPT (0.42) | MEN1KMT2AROCK2PIM1PIM3 | |
| SCHEMBL145426 | 0.80 | BIRC5 (0.44) | BIRC5ATM | |
| SCHEMBL6321218 | 0.79 | BIRC5 (0.51) | MGLLMEN1KMT2AROCK2PIM1 | |
| SCHEMBL16720387 | 0.78 | CFTR (0.38) | ROCK2PIM1PIM3F2F10 | |
| SCHEMBL16720474 | 0.77 | ROCK2 (0.55) | ROCK2PIM1PIM3F2F10 | |
| SCHEMBL16720477 | 0.73 | TDP2 (0.39) | ALDH1A1ATM | |
| SCHEMBL20180558 | 0.73 | MEN1 (0.39) | MGLLMEN1KMT2AROCK2PIM1 | |
| SCHEMBL16719505 | 0.71 | BIRC5 (0.39) | BIRC5CDC7CDK2ALDH1A1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2120569-A2 | SPIROCHROMANON DERIVATIVES | Merck & Co., Inc. (US) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008088692-A2 | SPIROCHROMANON DERIVATIVES | MERCK & CO., INC. (US) | 2008-07-24 | — | — | WO | disclosed |