SCHEMBL4276916

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4273798	0.89	PDE4A (0.42)	PDE4AFPR2PDE4BPDE4CPDE4D
	SCHEMBL4639480	0.87	PDE4A (0.41)	SMN1; SMN2PDE4AS1PR1S1PR3FPR2
	SCHEMBL4275742	0.84	SMN1; SMN2 (0.40)	SMN1; SMN2PDE4AS1PR1S1PR3FPR2
	SCHEMBL29813509	0.83	PDE4B (0.40)	SMN1; SMN2PDE4AS1PR1S1PR3FPR2
	SCHEMBL4275689	0.83	PDE4B (0.40)	SMN1; SMN2PDE4AS1PR1S1PR3FPR2
	SCHEMBL4640423	0.81	PDE4A (0.43)	PDE4AFPR2KDM4EHSD17B10MEN1
	SCHEMBL4639868	0.80	PDE4A (0.43)	PDE4AFPR2PDE4BPDE4CPDE4D
	SCHEMBL4275634	0.80	MEN1 (0.41)	SMN1; SMN2PDE4AS1PR1S1PR3FPR2
	SCHEMBL4275030	0.80	PDE4B (0.40)	SMN1; SMN2PDE4AS1PR1S1PR3FPR2
	SCHEMBL4280815	0.80	PDE4B (0.39)	SMN1; SMN2PDE4AS1PR1S1PR3FPR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.