SCHEMBL4273798

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4276916	0.89	SMN1; SMN2 (0.41)	PDE4AFPR2ABCB1ABCC1PDE4B
	SCHEMBL4640557	0.85	PDE4A (0.44)	PDE4AFPR2PDE4BLMNAPDE4C
	SCHEMBL4277672	0.82	PDE4B (0.41)	PDE4AFPR2PDE4BLMNAPDE4C
	SCHEMBL4271854	0.81	PIK3CG (0.45)	PIK3CGABCB1ABCC1LMNAMAPK1
	SCHEMBL4282936	0.80	FPR2 (0.44)	PDE4AFPR2ABCB1ABCC1PDE4B
	SCHEMBL4273090	0.80	FPR2 (0.44)	PDE4AFPR2ABCB1ABCC1PDE4B
	SCHEMBL4286025	0.79	PDE4B (0.40)	PDE4AFPR2PDE4BPDE4CPDE4D
	SCHEMBL4640423	0.79	PDE4A (0.43)	PDE4AFPR2PDE4BLMNAPDE4C
	SCHEMBL4284472	0.78	PDE4B (0.42)	PDE4AFPR2PDE4BLMNAL3MBTL1
	SCHEMBL4271328	0.78	PTGS2 (0.45)	PDE4AFPR2PDE4BLMNAPDE4C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.