Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 4/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | FPR2 | P25090 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4640423 | 0.95 | PDE4A (0.43) | PDE4APDE4BPDE4CPDE4DLMNA | |
| SCHEMBL4639868 | 0.93 | PDE4A (0.43) | PDE4APDE4BPDE4CPDE4DLMNA | |
| SCHEMBL4639383 | 0.90 | PDE4D (0.42) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4639471 | 0.90 | PDE4B (0.40) | PDE4APDE4BPDE4CPDE4DLMNA | |
| SCHEMBL4640557 | 0.90 | PDE4A (0.44) | PDE4APDE4BPDE4CPDE4DLMNA | |
| SCHEMBL4639456 | 0.89 | PDE4A (0.40) | PDE4APDE4BPDE4CPDE4DLMNA | |
| SCHEMBL4639422 | 0.88 | SMN1; SMN2 (0.42) | LMNAMAPTKDM4EUSP2HSD17B10 | |
| SCHEMBL4640052 | 0.87 | KDM4E (0.46) | LMNAKDM4EHSD17B10S1PR1S1PR3 | |
| SCHEMBL4276916 | 0.87 | SMN1; SMN2 (0.41) | PDE4APDE4BPDE4CPDE4DLMNA | |
| SCHEMBL4641238 | 0.85 | LMNA (0.41) | LMNAMAPTKDM4EUSP2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1954684-A2 | OXAZOLE COMPOUND AND PHARMACEUTICAL COMPOSITION | Otsuka Pharmaceutical Co., Ltd. (JP) | 2008-08-13 | — | — | EP | disclosed |
| WO-2007058338-A9 | OXAZOLE COMPOUND AND PHARMACEUTICAL COMPOSITION | OTSUKA PHARMA CO LTD (JP) | 2007-11-01 | — | — | WO | disclosed |
| WO-2007058338-A2 | OXAZOLE COMPOUND AND PHARMACEUTICAL COMPOSITION | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-05-24 | — | — | WO | disclosed |