Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 4/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.43 |
| ▸ | FPR2 | P25090 | 14/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4639471 | 0.97 | PDE4B (0.40) | PDE4APDE4BPDE4CPDE4DFPR2 | |
| SCHEMBL4639480 | 0.93 | PDE4A (0.41) | PDE4APDE4BPDE4CPDE4DFPR2 | |
| SCHEMBL4640423 | 0.93 | PDE4A (0.43) | PDE4APDE4BPDE4CPDE4DFPR2 | |
| SCHEMBL4639422 | 0.90 | SMN1; SMN2 (0.42) | FPR2LMNAMAPT | |
| SCHEMBL4640557 | 0.88 | PDE4A (0.44) | PDE4APDE4BPDE4CPDE4DFPR2 | |
| SCHEMBL4639603 | 0.88 | PDE4A (0.44) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4639456 | 0.88 | PDE4A (0.40) | PDE4APDE4BPDE4CPDE4DFPR2 | |
| SCHEMBL5592687 | 0.86 | FPR2 (0.37) | PDE4DFPR2LMNAMAPT | |
| SCHEMBL4641257 | 0.86 | FPR2 (0.37) | PDE4BFPR2 | |
| SCHEMBL4639429 | 0.85 | KDM4E (0.37) | LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1954684-A2 | OXAZOLE COMPOUND AND PHARMACEUTICAL COMPOSITION | Otsuka Pharmaceutical Co., Ltd. (JP) | 2008-08-13 | — | — | EP | disclosed |
| WO-2007058338-A2 | OXAZOLE COMPOUND AND PHARMACEUTICAL COMPOSITION | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-05-24 | — | — | WO | disclosed |