Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.47 |
| ▸ | MEN1 | O00255 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.45 |
| ▸ | MAPT | P10636 | 8/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | PTAFR | P25105 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4423144 | 0.84 | MAPT (0.49) | HPGDKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL4270390 | 0.84 | MEN1 (0.47) | HPGDKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL4266901 | 0.80 | RAB9A (0.48) | HPGDKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL4277728 | 0.79 | MEN1 (0.45) | HPGDKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL4274751 | 0.79 | MEN1 (0.45) | HPGDKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL4551674 | 0.74 | MAPT (0.37) | KMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL4272704 | 0.71 | SMN1; SMN2 (0.47) | HPGDKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL4268501 | 0.70 | GPR183 (0.49) | HPGDKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL791546 | 0.69 | HPGD (0.65) | HPGDKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL692257 | 0.69 | MEN1 (0.90) | HPGDKMT2AMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009110002-A1 | NOVEL EFFLUX PUMP INHIBITORS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2009-09-11 | — | — | WO | claimed |
| WO-2009110002-A1 | NOVEL EFFLUX PUMP INHIBITORS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2009-09-11 | — | — | WO | disclosed |