Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | MIF | P14174 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.34 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4419566 | 0.87 | CES1 (0.37) | MAPTCES1TRPM8GABRA1GABRB2 | |
| SCHEMBL4265182 | 0.86 | MAPT (0.46) | MAPTCES1GABRA1GABRB2AKR1B1 | |
| SCHEMBL4273001 | 0.82 | CYP1A2 (0.37) | TRPM8AKR1B1ACHEMEN1LMNA | |
| SCHEMBL4266901 | 0.80 | RAB9A (0.48) | MAPTCES1MEN1LMNACYP3A4 | |
| SCHEMBL4272704 | 0.79 | SMN1; SMN2 (0.47) | MAPTSMN1; SMN2ALOX5MEN1KMT2A | |
| SCHEMBL4412530 | 0.74 | MAPT (0.43) | MAPTCES1AKR1B1MEN1KMT2A | |
| SCHEMBL4412532 | 0.74 | MAPT (0.43) | MAPTCES1AKR1B1MEN1KMT2A | |
| SCHEMBL4277757 | 0.74 | HPGD (0.47) | MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL4266919 | 0.73 | MAPT (0.42) | MAPTMEN1LMNACYP3A4RECQL | |
| SCHEMBL4266849 | 0.72 | TRPM8 (0.36) | TRPM8GABRA1GABRB2MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009110002-A1 | NOVEL EFFLUX PUMP INHIBITORS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2009-09-11 | — | — | WO | claimed |