Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | APP | P05067 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | GPR183 | P32249 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4273945 | 0.84 | MITF (0.47) | MEN1KMT2ALMNAHPGDALDH1A1 | |
| SCHEMBL4270374 | 0.84 | MITF (0.47) | MEN1KMT2ALMNAHPGDALDH1A1 | |
| SCHEMBL4423144 | 0.79 | MAPT (0.49) | MEN1KMT2AGAAPOLBHPGD | |
| SCHEMBL4277757 | 0.79 | HPGD (0.47) | MEN1KMT2APOLBHPGDALDH1A1 | |
| SCHEMBL4270390 | 0.79 | MEN1 (0.47) | MEN1KMT2ALMNAGAAPOLB | |
| Pyrrolidine SCHEMBL4264339 | 0.79 | MITF (0.41) | MEN1KMT2ALMNAHPGDALDH1A1 | |
| SCHEMBL4273001 | 0.77 | CYP1A2 (0.37) | MEN1KMT2ALMNAALDH1A1RAB9A | |
| SCHEMBL4277728 | 0.77 | MEN1 (0.45) | MEN1KMT2AGAAPOLBHPGD | |
| SCHEMBL4271075 | 0.77 | LMNA (0.42) | MEN1KMT2ALMNAGAAHPGD | |
| SCHEMBL4264444 | 0.74 | ALDH1A1 (0.44) | MEN1KMT2ALMNAPOLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009110002-A1 | NOVEL EFFLUX PUMP INHIBITORS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2009-09-11 | — | — | WO | claimed |
| WO-2009110002-A1 | NOVEL EFFLUX PUMP INHIBITORS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2009-09-11 | — | — | WO | disclosed |