Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR183 | P32249 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4264341 | 0.94 | MEN1 (0.47) | GPR183MEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL4264349 | 0.79 | HCAR2 (0.44) | GPR183HPGDALDH1A1MAPTL3MBTL1 | |
| SCHEMBL4270776 | 0.79 | HCAR2 (0.44) | GPR183HPGDALDH1A1MAPTL3MBTL1 | |
| SCHEMBL4270404 | 0.76 | KMT2A (0.55) | MEN1KMT2AHPGDALDH1A1MAPT | |
| Pyrrole SCHEMBL4268503 | 0.72 | HDAC3 (0.38) | GPR183MEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL6785483 | 0.72 | KMT2A (0.51) | MEN1KMT2AHPGDALDH1A1MAPT | |
| SCHEMBL2531349 | 0.72 | GPR84 (0.41) | GPR183 | |
| SCHEMBL2531348 | 0.72 | GPR84 (0.41) | GPR183 | |
| SCHEMBL4544261 | 0.71 | HPGD (0.43) | MEN1KMT2AHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL4544262 | 0.71 | HPGD (0.43) | MEN1KMT2AHPGDALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009110002-A1 | NOVEL EFFLUX PUMP INHIBITORS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2009-09-11 | — | — | WO | claimed |
| WO-2009110002-A1 | NOVEL EFFLUX PUMP INHIBITORS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2009-09-11 | — | — | WO | disclosed |