Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 3/20 | 0.44 |
| ▸ | MMP1 | P03956 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3533238 | 0.82 | HDAC4 (0.43) | HDAC4SLC6A4SLC6A3SLC6A2AKR1C1 | |
| SCHEMBL4288043 | 0.76 | MMP1 (0.45) | MMP1SMN1; SMN2MMP2MMP3MEN1 | |
| SCHEMBL8234087 | 0.73 | SLC6A4 (0.46) | HDAC4SLC6A4SLC6A3SLC6A2AKR1C1 | |
| SCHEMBL6669439 | 0.73 | HDAC4 (0.49) | HDAC4SLC6A4SLC6A3SLC6A2AKR1C1 | |
| SCHEMBL28273316 | 0.72 | SLC6A4 (0.51) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL873930 | 0.71 | HDAC4 (0.41) | HDAC4SLC6A4SLC6A3SLC6A2AKR1C1 | |
| SCHEMBL6671640 | 0.71 | HDAC4 (0.47) | HDAC4SLC6A4SLC6A3SLC6A2AKR1C1 | |
| SCHEMBL16986558 | 0.70 | HDAC4 (0.40) | HDAC4SLC6A4SLC6A3SLC6A2AKR1C1 | |
| SCHEMBL28776197 | 0.70 | SLC6A4 (0.50) | HDAC4SLC6A4SLC6A3SLC6A2AKR1C1 | |
| SCHEMBL290573 | 0.70 | OPRM1 (0.46) | HDAC4SLC6A4SLC6A3SLC6A2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090253669-A1 | Substituted Sulfonamide Compounds | GRUENENTHAL GMBH (DE) | 2009-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090253669-A1 | Substituted Sulfonamide Compounds | SULT2A1, STS, SULT1A1 | HDAC4 2155/4885MMP1 4574/4885SLC6A4 986/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.