Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | RXRA | P19793 | 3/20 | 0.48 |
| ▸ | RXRB | P28702 | 3/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TPMT | P51580 | 1/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.46 |
| ▸ | KDM5A | P29375 | 1/20 | 0.46 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.46 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.46 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.46 |
| ▸ | RXRG | P48443 | 1/20 | 0.46 |
| ▸ | XDH | P47989 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4265171 | 0.88 | RXRA (0.62) | RXRARXRBMEN1KMT2ATPMT | |
| SCHEMBL4269670 | 0.86 | MEN1 (0.63) | THRATHRBRXRARXRBMEN1 | |
| SCHEMBL6731785 | 0.85 | NR4A2 (0.59) | RXRARXRBMAOBMEN1KMT2A | |
| SCHEMBL6720945 | 0.85 | NR4A2 (0.59) | RXRARXRBMAOBPARP10MEN1 | |
| SCHEMBL4274343 | 0.85 | RXRA (0.59) | RXRARXRBMAOBMEN1KMT2A | |
| SCHEMBL5014148 | 0.84 | RXRA (0.62) | RXRARXRBMEN1KMT2ATPMT | |
| SCHEMBL4275299 | 0.84 | MAOB (0.53) | THRATHRBMAOBMEN1KMT2A | |
| SCHEMBL29319558 | 0.81 | RXRA (0.62) | RXRARXRBRXRGNPC1POLB | |
| SCHEMBL4265195 | 0.81 | KDM5A (0.49) | RXRARXRBMAOBMEN1KMT2A | |
| SCHEMBL6725141 | 0.81 | RXRA (0.55) | RXRARXRBMAOBKDM5AKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066362-A1 | RADIOPAQUE AMIDE POLYMERS AND MEDICAL DEVICES FORMED THEREOF | Boston Scientific Limited (BB) | 2009-06-10 | — | — | EP | claimed |
| WO-2008033198-A1 | RADIOPAQUE AMIDE POLYMERS AND MEDICAL DEVICES FORMED THEREOF | BOSTON SCIENTIFIC LIMITED (BB) | 2008-03-20 | — | — | WO | claimed |
| US-20080064848-A1 | Radiopaque amide polymers and medical devices formed thereof | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2008-03-13 | — | — | US | claimed |
| US-6638977-B1 | Biaryl and benzyl ethers and thioethers | CORVAS INTERNATIONAL, INC. | 2003-10-28 | — | — | US | claimed |
| WO-2001036351-A2 | PLASMINOGEN ACTIVATOR INHIBITOR ANTAGONISTS RELATED APPLICATIONS | CORVAS INTERNATIONAL, INC. (US) | 2001-05-25 | — | — | WO | claimed |
| US-8507639-B2 | Polyamide block polymers containing iodoarylcarboxyl pendant groups and modified poly(meth)acrylamide; coupling; for tracking movement of a catheter through the body or inflation of balloon at site | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2013-08-13 | — | — | US | disclosed |
| US-20080064848-A1 | Radiopaque amide polymers and medical devices formed thereof | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2008-03-13 | — | — | US | disclosed |
| US-6677473-B1 | TREATMENT, PREVENTION OR AMELIORATION OF ONE OR MORE SYMPTOMS OF THROMBOTIC DISORDERS, UNSTABLE ANGINA OR CANCER | CORVAS INTERNATIONAL INC | 2004-01-13 | — | — | US | disclosed |
| WO-2001036351-A2 | PLASMINOGEN ACTIVATOR INHIBITOR ANTAGONISTS RELATED APPLICATIONS | CORVAS INTERNATIONAL, INC. (US) | 2001-05-25 | — | — | WO | disclosed |