Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 5/20 | 0.62 |
| ▸ | RXRB | P28702 | 5/20 | 0.62 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.62 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.60 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.60 |
| ▸ | RXRG | P48443 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | APP | P05067 | 1/20 | 0.49 |
| ▸ | XDH | P47989 | 2/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TPMT | P51580 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6725141 | 0.86 | RXRA (0.55) | RXRARXRBNR4A2RXRGMRGPRX4 | |
| SCHEMBL4278599 | 0.84 | THRA (0.50) | RXRARXRBRXRGRAB9AXDH | |
| SCHEMBL4265171 | 0.84 | RXRA (0.62) | RXRARXRBNR4A2RAB9AAPP | |
| SCHEMBL6723656 | 0.83 | RXRA (0.64) | RXRARXRBNR4A2NR4A1NR4A3 | |
| SCHEMBL4272450 | 0.83 | RXRA (0.62) | RXRARXRBNR4A2NR4A1NR4A3 | |
| SCHEMBL6728526 | 0.83 | RXRA (0.51) | RXRARXRBNR4A2NR4A1NR4A3 | |
| SCHEMBL6723445 | 0.82 | RXRA (0.60) | RXRARXRBNR4A2NR4A1NR4A3 | |
| SCHEMBL4269670 | 0.82 | MEN1 (0.63) | RXRARXRBNR4A2NR4A1NR4A3 | |
| SCHEMBL6731785 | 0.81 | NR4A2 (0.59) | RXRARXRBNR4A2RXRGRAB9A | |
| SCHEMBL4274343 | 0.81 | RXRA (0.59) | RXRARXRBAPPXDHMRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080064848-A1 | Radiopaque amide polymers and medical devices formed thereof | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2008-03-13 | — | — | US | claimed |
| US-6638977-B1 | Biaryl and benzyl ethers and thioethers | CORVAS INTERNATIONAL, INC. | 2003-10-28 | — | — | US | claimed |
| WO-2001036351-A2 | PLASMINOGEN ACTIVATOR INHIBITOR ANTAGONISTS RELATED APPLICATIONS | CORVAS INTERNATIONAL, INC. (US) | 2001-05-25 | — | — | WO | claimed |
| US-8507639-B2 | Polyamide block polymers containing iodoarylcarboxyl pendant groups and modified poly(meth)acrylamide; coupling; for tracking movement of a catheter through the body or inflation of balloon at site | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2013-08-13 | — | — | US | disclosed |
| US-20080064848-A1 | Radiopaque amide polymers and medical devices formed thereof | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2008-03-13 | — | — | US | disclosed |
| US-6677473-B1 | TREATMENT, PREVENTION OR AMELIORATION OF ONE OR MORE SYMPTOMS OF THROMBOTIC DISORDERS, UNSTABLE ANGINA OR CANCER | CORVAS INTERNATIONAL INC | 2004-01-13 | — | — | US | disclosed |
| WO-2003009871-A2 | INHIBITORS OF PLASMINOGEN ACTIVATOR INHIBITOR FOR DECREASING BODY MASS | GENSET S.A. (FR) | 2003-02-06 | — | — | WO | disclosed |
| WO-2001036351-A2 | PLASMINOGEN ACTIVATOR INHIBITOR ANTAGONISTS RELATED APPLICATIONS | CORVAS INTERNATIONAL, INC. (US) | 2001-05-25 | — | — | WO | disclosed |