SCHEMBL4279745

SCHEMBL4279745

CC(=O)OCc1cc(O)c(C(=O)c2ccc(OC3CC3)cc2)c(Cl)c1

nearest known ligand 0.39

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PARP10 Q53GL7 1/20 0.39
EPHX2 P34913 11/20 0.38
FAAH O00519 4/20 0.38
RAF1 P04049 2/20 0.38
MAP4K4 O95819 1/20 0.37
RORC P51449 1/20 0.36
MEN1 O00255 4/20 0.36
KMT2A Q03164 4/20 0.36
MAPK1 P28482 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
ADRB2 P07550 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4288165 0.85 ALDH1A1 (0.48) PARP10KMT2AMAPK1SMN1; SMN2
SCHEMBL4283882 0.85 PARP10 (0.43) PARP10EPHX2FAAHRAF1MAP4K4
SCHEMBL4285302 0.85 HPGD (0.46) RAF1MEN1KMT2AMAPK1SMN1; SMN2
SCHEMBL4281489 0.82 ACACB (0.36) EPHX2RAF1RORCMEN1KMT2A
SCHEMBL4281420 0.81 ACACB (0.37) RORCMEN1KMT2A
SCHEMBL4285539 0.80 MAP4K4 (0.45) PARP10EPHX2FAAHRAF1MAP4K4
SCHEMBL4288478 0.74 CYP3A4 (0.45) PARP10MEN1KMT2A
SCHEMBL4284453 0.74 THRA (0.39) PARP10
SCHEMBL4279710 0.74 MAOB (0.48) PARP10KMT2AMAPK1SMN1; SMN2
SCHEMBL4289375 0.73 HTR2A (0.41) ADRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090137499-A1 BENZYLPHENYL GLUCOPYRANOSIDE DERIVATIVE DAIICHI SANKYO COMPANY, LIMITED (JP) 2009-05-28 US disclosed
EP-2048150-A1 BENZYL PHENYL GLUCOPYRANOSIDE DERIVATIVE Daiichi Sankyo Company, Limited (JP) 2009-04-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090137499-A1 BENZYLPHENYL GLUCOPYRANOSIDE DERIVATIVE SLC5A1, SLC5A2, SLC2A1 PARP10 2557/4885EPHX2 4388/4885FAAH 2640/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.