SCHEMBL4285539

SCHEMBL4285539

Cc1cc(O)c(C(=O)c2ccc(OC3CC3)cc2)c(Cl)c1

nearest known ligand 0.45

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MAP4K4 O95819 1/20 0.45
PARP10 Q53GL7 1/20 0.44
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
EPHX2 P34913 13/20 0.40
FAAH O00519 2/20 0.40
RAF1 P04049 2/20 0.39
SENP8 Q96LD8 1/20 0.38
SENP6 Q9GZR1 1/20 0.38
LSS P48449 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4282822 0.84 RORC (0.41) MAP4K4PARP10MEN1KMT2AEPHX2
SCHEMBL4283882 0.82 PARP10 (0.43) MAP4K4PARP10MEN1KMT2AEPHX2
SCHEMBL4283897 0.82 HPGD (0.54) PARP10MEN1KMT2ARAF1
SCHEMBL4289278 0.81 MAPT (0.51) PARP10KMT2A
SCHEMBL4279745 0.80 PARP10 (0.39) MAP4K4PARP10MEN1KMT2AEPHX2
SCHEMBL4294425 0.73 EPHX2 (0.51) MAP4K4PARP10MEN1KMT2AEPHX2
SCHEMBL4285685 0.73 EPHX2 (0.50) MAP4K4PARP10MEN1KMT2AEPHX2
SCHEMBL24799517 0.69 PARP10 (0.54) MAP4K4PARP10EPHX2FAAHSENP8
SCHEMBL10313059 0.69 ELANE (0.60) PARP10MEN1KMT2AEPHX2FAAH
SCHEMBL25106987 0.69 LMNA (0.46) MAP4K4PARP10MEN1KMT2AEPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090137499-A1 BENZYLPHENYL GLUCOPYRANOSIDE DERIVATIVE DAIICHI SANKYO COMPANY, LIMITED (JP) 2009-05-28 US disclosed
EP-2048150-A1 BENZYL PHENYL GLUCOPYRANOSIDE DERIVATIVE Daiichi Sankyo Company, Limited (JP) 2009-04-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090137499-A1 BENZYLPHENYL GLUCOPYRANOSIDE DERIVATIVE SLC5A1, SLC5A2, SLC2A1 MAP4K4 1470/4885PARP10 2557/4885MEN1 3776/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.