Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.62 |
| ▸ | RAB9A | P51151 | 10/20 | 0.61 |
| ▸ | NPC1 | O15118 | 8/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.61 |
| ▸ | MEN1 | O00255 | 10/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | HPGD | P15428 | 5/20 | 0.59 |
| ▸ | TP53 | P04637 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | PLEC | Q15149 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL619636 | 0.85 | RAB9A (0.62) | POLBRAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL4280113 | 0.83 | RAB9A (0.61) | POLBRAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL15001259 | 0.83 | RAB9A (0.65) | POLBRAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL892506 | 0.83 | POLB (0.62) | POLBRAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL9911643 | 0.81 | RAB9A (0.70) | POLBRAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL15001254 | 0.80 | RAB9A (0.68) | POLBRAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL9911623 | 0.80 | RAB9A (0.72) | POLBRAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL20507129 | 0.80 | KMT2A (0.71) | POLBRAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL9911644 | 0.80 | RAB9A (0.60) | POLBRAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL9911645 | 0.76 | RAB9A (0.77) | POLBRAB9ANPC1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090143451-A1 | COMPOUNDS THAT INCREASE TELOMERASE REVERSE TRANSCRIPTASE (TERT) EXPRESSION AND METHODS FOR USING THE SAME | SIERRA SCIENCES INC. | 2009-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090143451-A1 | COMPOUNDS THAT INCREASE TELOMERASE REVERSE TRANSCRIPTASE (TERT) EXPRESSION AND METHODS FOR USING THE SAME | TERT, TERF2, RNMT | POLB 24/4885RAB9A 3970/4885NPC1 2996/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.