Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 5/20 | 0.57 |
| ▸ | PDE4A | P27815 | 12/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 12/20 | 0.50 |
| ▸ | PDE4C | Q08493 | 12/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 12/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 7/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | CDK1 | P06493 | 2/20 | 0.44 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.44 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.43 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6272301 | 0.94 | ADORA2B (0.64) | ADORA2BPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4384741 | 0.94 | ADORA2B (0.64) | ADORA2BPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8536009 | 0.94 | ADORA2B (0.64) | ADORA2BPDE4APDE4BPDE4CPDE4D | |
| Hydrochloric Acid SCHEMBL258898 | 0.93 | ADORA2B (0.62) | ADORA2BPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8522275 | 0.93 | ADORA2B (0.61) | ADORA2BPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6272735 | 0.89 | PDE4A (0.59) | ADORA2BPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL667797 | 0.84 | PDE4A (0.60) | ADORA2BPDE4APDE4BPDE4CPDE4D | |
| Acetic Acid SCHEMBL4280715 | 0.81 | ADORA2B (0.48) | ADORA2BPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL28721443 | 0.79 | CDK1 (0.53) | ADORA2BPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6265343 | 0.79 | PDE4A (0.55) | ADORA2BPDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090133810-A1 | Production method and filter comprising non woven fabric and/or filtering injector structures or sheets which are obtained using said method and which are intended for the filtration and elimination of legionella pneumophila in any installation at risk from legionella pneumophila proliferation | PENALVA JOAQUIN ESPUELAS | 2009-05-28 | — | — | US | claimed |
| US-20070202770-A1 | Production Method and Filter Comprising Non Woven Fabric and/or Filtering Injector Structures or Sheets Which are Obtained Using Said Method and Which are Intended for the Filtration and Which are Intended for the Filtration and Elimination of Legionella Pneumofila in any Installation at Risk From Legionella Pneumofila Proliferation | PENALVA JOAQUIN E | 2007-08-30 | — | — | US | claimed |
| EP-1738812-A1 | PRODUCTION METHOD, AND FILTER COMPRISING NON-WOVEN FABRIC AND/OR FILTERING INJECTOR STRUCTURES OR SHEETS WHICH ARE OBTAINED USING SAID METHOD AND WHICH ARE INTENDED FOR THE FILTRATION AND ELIMINATION OF LEGIONELLA PNEUMOPHILA IN ANY INSTALLATION WITH A RISK OF LEGIONELLA PNEUMOPHILA PROLIFERATION | Espuelas Peñalva, Joaquin (ES) | 2007-01-03 | — | — | EP | claimed |
| CN-1938072-B | Filter and method for manufacturing the same | ESPUELAS PENALVA JOAQUIN (ES) | 2011-12-14 | — | — | CN | disclosed |
| US-20090133810-A1 | Production method and filter comprising non woven fabric and/or filtering injector structures or sheets which are obtained using said method and which are intended for the filtration and elimination of legionella pneumophila in any installation at risk from legionella pneumophila proliferation | PENALVA JOAQUIN ESPUELAS | 2009-05-28 | — | — | US | disclosed |
| US-20070202770-A1 | Production Method and Filter Comprising Non Woven Fabric and/or Filtering Injector Structures or Sheets Which are Obtained Using Said Method and Which are Intended for the Filtration and Which are Intended for the Filtration and Elimination of Legionella Pneumofila in any Installation at Risk From Legionella Pneumofila Proliferation | PENALVA JOAQUIN E | 2007-08-30 | — | — | US | disclosed |
| CN-1938072-A | Method for the production and filter obtained using said method, comprising a nonwoven and/or filter injector structure or sheet and used for filtering and removing legionella pneumophila from any equipment at risk of its proliferation | JOAQUIN ESPUELAS PENALVA (ES) | 2007-03-28 | — | — | CN | disclosed |
| EP-1738812-A1 | PRODUCTION METHOD, AND FILTER COMPRISING NON-WOVEN FABRIC AND/OR FILTERING INJECTOR STRUCTURES OR SHEETS WHICH ARE OBTAINED USING SAID METHOD AND WHICH ARE INTENDED FOR THE FILTRATION AND ELIMINATION OF LEGIONELLA PNEUMOPHILA IN ANY INSTALLATION WITH A RISK OF LEGIONELLA PNEUMOPHILA PROLIFERATION | Espuelas Peñalva, Joaquin (ES) | 2007-01-03 | — | — | EP | disclosed |