Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 7/20 | 0.64 |
| ▸ | PDE4A | P27815 | 12/20 | 0.53 |
| ▸ | PDE4B | Q07343 | 12/20 | 0.53 |
| ▸ | PDE4C | Q08493 | 12/20 | 0.53 |
| ▸ | PDE4D | Q08499 | 12/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 10/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | CDK1 | P06493 | 2/20 | 0.49 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.49 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.47 |
| ▸ | CDK2 | P24941 | 1/20 | 0.47 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.47 |
| ▸ | XDH | P47989 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6272301 | 1.00 | ADORA2B (0.64) | ADORA2BPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4384741 | 1.00 | ADORA2B (0.64) | ADORA2BPDE4APDE4BPDE4CPDE4D | |
| Hydrochloric Acid SCHEMBL258898 | 0.99 | ADORA2B (0.62) | ADORA2BPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8522275 | 0.99 | ADORA2B (0.61) | ADORA2BPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6272735 | 0.95 | PDE4A (0.59) | ADORA2BPDE4APDE4BPDE4CPDE4D | |
| Acetic Acid SCHEMBL4280720 | 0.94 | ADORA2B (0.57) | ADORA2BPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL667797 | 0.89 | PDE4A (0.60) | ADORA2BPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL28721443 | 0.84 | CDK1 (0.53) | ADORA2BPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL874737 | 0.83 | ADORA2A (0.56) | ADORA2BPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3671339 | 0.81 | DPP4 (0.44) | ADORA2BPDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0794781-A4 | DRUGS TO PREVENT RECURRENT HERPES VIRUS INFECTIONS | UNIV MASSACHUSETTS MEDICAL (US) | 1998-04-22 | — | — | EP | disclosed |
| EP-0794781-A1 | DRUGS TO PREVENT RECURRENT HERPES VIRUS INFECTIONS | UNIVERSITY OF MASSACHUSETTS MEDICAL CENTER (US) | 1997-09-17 | — | — | EP | disclosed |
| WO-1996020711-A1 | DRUGS TO PREVENT RECURRENT HERPES VIRUS INFECTIONS | UNIVERSITY OF MASSACHUSETTS MEDICAL CENTER (US) | 1996-07-11 | — | — | WO | disclosed |