SCHEMBL4384741

SCHEMBL4384741

CCCCCCn1c(N)nc2nc[nH]c2c1=O

nearest known ligand 0.64

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ADORA2B P29275 7/20 0.64
PDE4A P27815 12/20 0.53
PDE4B Q07343 12/20 0.53
PDE4C Q08493 12/20 0.53
PDE4D Q08499 12/20 0.53
ADORA2A P29274 10/20 0.53
ADORA3 P0DMS8 1/20 0.50
CDK1 P06493 2/20 0.49
CCNB1 P14635 2/20 0.49
CCNA2 P20248 1/20 0.47
CDK2 P24941 1/20 0.47
CCNA1 P78396 1/20 0.47
XDH P47989 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8536009 1.00 ADORA2B (0.64) ADORA2BPDE4APDE4BPDE4CPDE4D
SCHEMBL6272301 1.00 ADORA2B (0.64) ADORA2BPDE4APDE4BPDE4CPDE4D
Hydrochloric Acid SCHEMBL258898 0.99 ADORA2B (0.62) ADORA2BPDE4APDE4BPDE4CPDE4D
SCHEMBL8522275 0.99 ADORA2B (0.61) ADORA2BPDE4APDE4BPDE4CPDE4D
SCHEMBL6272735 0.95 PDE4A (0.59) ADORA2BPDE4APDE4BPDE4CPDE4D
Acetic Acid SCHEMBL4280720 0.94 ADORA2B (0.57) ADORA2BPDE4APDE4BPDE4CPDE4D
SCHEMBL667797 0.89 PDE4A (0.60) ADORA2BPDE4APDE4BPDE4CPDE4D
SCHEMBL28721443 0.84 CDK1 (0.53) ADORA2BPDE4APDE4BPDE4CPDE4D
SCHEMBL874737 0.83 ADORA2A (0.56) ADORA2BPDE4APDE4BPDE4CPDE4D
SCHEMBL3671339 0.81 DPP4 (0.44) ADORA2BPDE4APDE4BPDE4CPDE4D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12279614-B2 Photo-polymerizable, universal antimicrobial coating to produce high-performing, multi-functional face masks THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) 2025-04-22 US disclosed
US-20230337670-A1 PHOTO-POLYMERIZABLE, UNIVERSAL ANTIMICROBIAL COATING TO PRODUCE HIGH-PERFORMING, MULTI-FUNCTIONAL FACE MASKS THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) 2023-10-26 US disclosed
WO-2009043899-A1 DRUG TRANSFER INTO LIVING CELLS COVALYS BIOSCIENCES AG (CH) 2009-04-09 WO disclosed
JP-2001055528-A RECEPTIVE INK AND PRINTING SUBSTRATE AND PRINTING ARTICLE USING SAME TEIKOKU PRINTING INKS MFG CO LTD 2001-02-27 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12279614-B2 Photo-polymerizable, universal antimicrobial coating to produce high-performing, multi-functional face masks CUTA, PUF60, PARN ADORA2B 4811/4885PDE4A 4354/4885PDE4B 4517/4885
US-20230337670-A1 PHOTO-POLYMERIZABLE, UNIVERSAL ANTIMICROBIAL COATING TO PRODUCE HIGH-PERFORMING, MULTI-FUNCTIONAL FACE MASKS CUTA, PUF60, PARN ADORA2B 4811/4885PDE4A 4354/4885PDE4B 4517/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.