SCHEMBL4280908

SCHEMBL4280908

O=C(NCCO)C(Cl)(Cl)Cl

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.43
ALDH1A1 P00352 7/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
USP2 O75604 1/20 0.42
MAPT P10636 1/20 0.42
POLB P06746 2/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
HPGD P15428 1/20 0.34
HTT P42858 1/20 0.34
CNR1 P21554 2/20 0.34
CA3 P07451 2/20 0.32
CA5A P35218 2/20 0.32
CA5B Q9Y2D0 2/20 0.32
L3MBTL1 Q9Y468 2/20 0.32
CA12 O43570 1/20 0.32
CA2 P00918 1/20 0.32
CA4 P22748 1/20 0.32
CA6 P23280 1/20 0.32
CA7 P43166 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13660344 0.79 MEN1 (0.58) LMNAALDH1A1MEN1KMT2APOLB
SCHEMBL13660345 0.79 MEN1 (0.58) LMNAALDH1A1MEN1KMT2APOLB
SCHEMBL13660337 0.79 MEN1 (0.58) LMNAALDH1A1MEN1KMT2APOLB
SCHEMBL10953486 0.79 LMNA (0.43) LMNAALDH1A1MEN1KMT2AMAPT
SCHEMBL4948924 0.78
SCHEMBL21487547 0.77 ALDH1A1 (0.46) LMNAALDH1A1MEN1KMT2AUSP2
SCHEMBL2797759 0.77 MMP1 (0.43) LMNAALDH1A1MEN1KMT2APOLB
SCHEMBL11592861 0.75 LMNA (0.49) LMNAALDH1A1MEN1KMT2APOLB
SCHEMBL8912326 0.75 LMNA (0.41) LMNAALDH1A1MEN1KMT2APOLB
SCHEMBL13660338 0.75 TSHR (0.50) LMNAALDH1A1MEN1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0974557-B1 Method for forming article using sol-gel processing LUCENT TECHNOLOGIES INC (US) 2002-10-02 EP claimed
US-6209357-B1 AGING A SILICA DISPERSION WITH TETRAALKYLAMMONIUM HYDROXYDE STABILIZING AGENT,ADJUSTING THE ISOELECTRIC POINT TO9.0 OR HIGHER BY ADDING AMMONIUM HYDROXIDE OR AMINES;INDUCING GELATION AND DRYING;SILICA BODY OPTICAL FIBER PREFORM LUCENT TECHNOLOGIES INC. 2001-04-03 US claimed
EP-0974557-A1 Method for forming article using sol-gel processing LUCENT TECHNOLOGIES INC. (US) 2000-01-26 EP claimed
US-4318861-A N-HYDROXYALKYL CHLOROALKANOIC ACID AMIDES ATLANTIC RICHFIELD COMPANY (US) 1982-03-09 US claimed
EP-2088128-B1 Method for the production of glassy monoliths via the sol-gel process CRISTAL MATERIALS CORP (TW) 2015-04-08 EP disclosed
CN-103553299-A Sol-gel process EVONIK DEGUSSA GMBH 2014-02-05 CN disclosed
CN-101456665-B Method for the production of glassy monoliths via the sol-gel process EVONIK DEGUSSA GMBH 2012-03-21 CN disclosed
US-20090293544-A1 Method for the production of glassy monoliths via the sol-gel process EVONIK DEGUSSA GMBH (DE) 2009-12-03 US disclosed
US-20090205370-A1 SOL-GEL PROCESS EVONIK DEGUSSA GMBH (DE) 2009-08-20 US disclosed
CN-101511746-A Sol-gel process GEGUSSA NOVARA TECHNOLOGY SPA (IT) 2009-08-19 CN disclosed
EP-2088128-A1 Method for the production of glassy monoliths via the sol-gel process Degussa Novara Technology S.p.A. (IT) 2009-08-12 EP disclosed
CN-101456665-A Method for the production of glassy monoliths via the sol-gel process GEGUSSA NOVARA TECHNOLOGY SPA (IT) 2009-06-17 CN disclosed
US-20070020555-A1 Photosensitive composition, photosensitive lithography plate and method for producing lithography plate KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2007-01-25 US disclosed
EP-1167308-B1 Sol-gel process for fabricating germanium-doped silica article LUCENT TECHNOLOGIES INC (US) 2003-05-07 EP disclosed
EP-0974557-B1 Method for forming article using sol-gel processing LUCENT TECHNOLOGIES INC (US) 2002-10-02 EP disclosed
US-6442977-B1 Sol-gel process for fabricating germanium-doped silica article FITEL USA CORP. 2002-09-03 US disclosed
EP-1167308-A1 Sol-gel process for fabricating germanium-doped silica article LUCENT TECHNOLOGIES INC. (US) 2002-01-02 EP disclosed
US-6209357-B1 AGING A SILICA DISPERSION WITH TETRAALKYLAMMONIUM HYDROXYDE STABILIZING AGENT,ADJUSTING THE ISOELECTRIC POINT TO9.0 OR HIGHER BY ADDING AMMONIUM HYDROXIDE OR AMINES;INDUCING GELATION AND DRYING;SILICA BODY OPTICAL FIBER PREFORM LUCENT TECHNOLOGIES INC. 2001-04-03 US disclosed
EP-0974557-A1 Method for forming article using sol-gel processing LUCENT TECHNOLOGIES INC. (US) 2000-01-26 EP disclosed
US-4318861-A N-HYDROXYALKYL CHLOROALKANOIC ACID AMIDES ATLANTIC RICHFIELD COMPANY (US) 1982-03-09 US disclosed