SCHEMBL4281206

SCHEMBL4281206

C=CCn1cc[n+](C)c1.CS(=O)(=O)[O-]

nearest known ligand 0.40

Known targets — ChEMBL curated mechanism

ABL1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB2AGTR1BCL2BCL2A1BCL2L1BCL2L10BCL2L2BCRBRAFCHRM1CHRNA10CHRNA9DRD1DRD2DRD3DRD4DRD5EGFRF2FLT1FLT4GCKGHSRGNRHRGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHTR1AHTR1BHTR1DHTR2AHTR2CHTR3AIDH2KDRKITMAOBMCL1MTTPPP4HBPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PIKFYVEROCK1ROCK2SLC18A2SLC6A2SLC6A3SLC6A4TACR1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8gyrAgyrBparCparEpol

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FDPS P14324 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.37
MAPT P10636 2/20 0.37
NPSR1 Q6W5P4 2/20 0.37
MEN1 O00255 1/20 0.37
APAF1 O14727 1/20 0.37
NPC1 O15118 1/20 0.37
PLA2G1B P04054 1/20 0.37
HSP90AA1 P07900 1/20 0.37
MAPK1 P28482 1/20 0.37
HTT P42858 1/20 0.37
RAB9A P51151 1/20 0.37
KMT2A Q03164 1/20 0.37
ATG4B Q9Y4P1 1/20 0.37
LMNA P02545 2/20 0.33
TP53 P04637 1/20 0.30
THRB P10828 1/20 0.30
RECQL P46063 1/20 0.30
BLM P54132 1/20 0.30
ATM Q13315 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfuric Acid SCHEMBL30712585 0.95 FDPS (0.39) FDPSSMN1; SMN2MAPTNPSR1MEN1
Sulfuric Acid SCHEMBL1101232 0.92 FDPS (0.40) FDPSSMN1; SMN2MAPTNPSR1MEN1
SCHEMBL9934092 0.89 FDPS (0.38) FDPSSMN1; SMN2MAPTNPSR1MEN1
SCHEMBL14635383 0.89 FDPS (0.35) FDPSSMN1; SMN2MAPTNPSR1MEN1
Sulfuric Acid SCHEMBL28517102 0.88 FDPS (0.39) FDPSSMN1; SMN2MAPTNPSR1MEN1
Trifluoromethanesulfonic Acid SCHEMBL4920095 0.88 FDPS (0.37) FDPSSMN1; SMN2MAPTNPSR1MEN1
SCHEMBL205339 0.88
Formic Acid SCHEMBL17076871 0.86 FDPS (0.40) FDPSSMN1; SMN2MAPTNPSR1MEN1
Hydrochloric Acid SCHEMBL59757 0.86 SMN1; SMN2 (0.43) FDPSSMN1; SMN2MAPTNPSR1MEN1
Iodide SCHEMBL898865 0.86 MEN1 (0.43) FDPSSMN1; SMN2MAPTNPSR1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9862982-B2 Methods of hydrolyzing a cellulose using halophilic, thermostable and ionic liquids tolerant cellulases THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2018-01-09 US claimed
US-20170029856-A1 Useful halophilic, thermostable and ionic liquids tolerant cellulases THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2017-02-02 US claimed
US-20130023015-A1 Useful halophilic, thermostable and ionic liquids tolerant cellulases THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2013-01-24 US claimed
US-20250372685-A1 METHOD FOR PREPARING AN ION EXCHANGE MEMBRANE UNIV GRAZ TECH (AT) 2025-12-04 US disclosed
EP-4543970-A1 METHOD FOR PREPARING AN ION EXCHANGE MEMBRANE Ecolyte GmbH (AT) 2025-04-30 EP disclosed
WO-2023247756-A1 METHOD FOR PREPARING AN ION EXCHANGE MEMBRANE TECHNISCHE UNIVERSITÄT GRAZ (AT) 2023-12-28 WO disclosed
US-9862982-B2 Methods of hydrolyzing a cellulose using halophilic, thermostable and ionic liquids tolerant cellulases THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2018-01-09 US disclosed
US-20170029856-A1 Useful halophilic, thermostable and ionic liquids tolerant cellulases THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2017-02-02 US disclosed
US-9376728-B2 Useful halophilic, thermostable and ionic liquids tolerant cellulases THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2016-06-28 US disclosed
US-20130023015-A1 Useful halophilic, thermostable and ionic liquids tolerant cellulases THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2013-01-24 US disclosed
US-7605271-B2 Superhigh purity ionic liquid DAI-ICHI KOGYO SEIYAKU CO., LTD (JP) 2009-10-20 US disclosed
US-20060223995-A1 Superhigh purity ionic liquid DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) 2006-10-05 US disclosed
EP-1707265-A1 Superhigh purity ionic liquid DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) 2006-10-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060223995-A1 Superhigh purity ionic liquid SLC7A5, SLC7A1, SLC43A1 FDPS 4271/4885SMN1; SMN2 2773/4885MAPT 4184/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.