Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 6/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 3/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4274822 | 0.86 | CES1 (0.43) | CES1ACHEKCNN4NR1H2NR1H3 | |
| SCHEMBL1053099 | 0.84 | CES1 (0.42) | CES1ACHEKCNN4NR1H2NR1H3 | |
| SCHEMBL15796967 | 0.82 | CES1 (0.37) | CES1ACHEKCNN4NR1H2NR1H3 | |
| SCHEMBL1051530 | 0.81 | ACHE (0.41) | CES1ACHEKCNN4NR1H2NR1H3 | |
| SCHEMBL4273955 | 0.81 | ACHE (0.41) | CES1ACHEKCNN4NR1H2NR1H3 | |
| SCHEMBL4270175 | 0.80 | CYP1A2 (0.38) | CES1KCNN4ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL10606240 | 0.78 | KCNN4 (0.55) | CES1KCNN4HDAC1HDAC2HDAC6 | |
| SCHEMBL704615 | 0.75 | CES2 (0.41) | CES1NR1H2NR1H3ALDH1A1MAPT | |
| SCHEMBL132756 | 0.72 | CES2 (0.43) | CES1ALDH1A1MAPTSMN1; SMN2ESR1 | |
| SCHEMBL21399435 | 0.71 | CES1 (0.37) | CES1ACHENR1H2NR1H3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8716417-B2 | Olefin polymerization catalyst and preparation method and use thereof | PETROCHINA COMPANY LIMITED (CN) | 2014-05-06 | — | — | US | claimed |
| US-8716417-B2 | Olefin polymerization catalyst and preparation method and use thereof | PETROCHINA COMPANY LIMITED (CN) | 2014-05-06 | — | — | US | disclosed |
| US-7604866-B2 | Comprising silica particles and at least one binder compound; good mechanical strength and abrasion resistance | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2009-10-20 | — | — | US | disclosed |
| US-20060269724-A1 | Comprising silica particles and at least one binder compound; good mechanical strength and abrasion resistance | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2006-11-30 | — | — | US | disclosed |