Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 2/20 | 0.30 |
| ▸ | CES1 | P23141 | 2/20 | 0.30 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4266443 | 0.84 | CYP1A2 (0.38) | CYP1A2ALDH1A1HPGDKDM4EGLA | |
| SCHEMBL4272735 | 0.84 | CYP1A2 (0.38) | CYP1A2ALDH1A1HPGDKDM4EGLA | |
| SCHEMBL4266017 | 0.81 | KCNN4 (0.36) | CYP1A2ALDH1A1HPGDKDM4EGLA | |
| SCHEMBL4281419 | 0.80 | CES1 (0.42) | ALDH1A1SMN1; SMN2KCNN4MAPTCES1 | |
| SCHEMBL10606240 | 0.78 | KCNN4 (0.55) | CYP1A2KCNN4KMT2AMEN1MAPT | |
| SCHEMBL132756 | 0.72 | CES2 (0.43) | CYP1A2ALDH1A1HPGDKDM4EGAA | |
| SCHEMBL704615 | 0.71 | CES2 (0.41) | ALDH1A1HPGDKDM4EGAASMN1; SMN2 | |
| SCHEMBL987567 | 0.68 | ELANE (0.47) | CYP1A2ALDH1A1HPGDKDM4EATM | |
| SCHEMBL21925797 | 0.68 | THRB (0.43) | ALDH1A1HPGDKDM4ESMN1; SMN2KMT2A | |
| SCHEMBL1943281 | 0.68 | ELANE (0.46) | ALDH1A1HPGDKDM4EATMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7604866-B2 | Comprising silica particles and at least one binder compound; good mechanical strength and abrasion resistance | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2009-10-20 | — | — | US | disclosed |
| US-20060269724-A1 | Comprising silica particles and at least one binder compound; good mechanical strength and abrasion resistance | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2006-11-30 | — | — | US | disclosed |