Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.31 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.31 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL150661 | 0.72 | NQO1 (0.33) | NQO1 | |
| SCHEMBL14587482 | 0.71 | ALOX5 (0.51) | NQO1ALOX5SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL3997148 | 0.69 | — | — | |
| SCHEMBL20214427 | 0.66 | ADORA2B (0.31) | — | |
| SCHEMBL29501710 | 0.64 | SMN1; SMN2 (0.48) | NQO1 | |
| SCHEMBL28874743 | 0.62 | KMT2A (0.51) | — | |
| SCHEMBL1841418 | 0.60 | MAOB (0.50) | — | |
| SCHEMBL27460313 | 0.59 | MAPT (0.36) | NQO1 | |
| SCHEMBL4287833 | 0.59 | ALOX15 (0.40) | NQO1 | |
| SCHEMBL30437401 | 0.59 | KMT2A (0.50) | NQO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009151683-A2 | QUINOLINONE FARNESYL TRANSFERASE INHIBITORS FOR THE TREATMENT OF SYNUCLEINOPATHIES AND OTHER INDICATIONS | LINK MEDICINE CORPORATION (US) | 2009-12-17 | — | — | WO | disclosed |