Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | CASP6 | P55212 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | NT5E | P21589 | 2/20 | 0.42 |
| ▸ | TIMP3 | P35625 | 4/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.37 |
| ▸ | NSD2 | O96028 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11568447 | 0.83 | ALDH1A1 (0.57) | HSD17B10ALDH1A1CASP6CYP2C9CYP2C19 | |
| SCHEMBL3217157 | 0.79 | AURKA (0.58) | HSD17B10ALDH1A1CASP6CYP2C9CYP2C19 | |
| SCHEMBL19578716 | 0.79 | TIMP3 (0.42) | HSD17B10ALDH1A1CASP6CYP2C9CYP2C19 | |
| SCHEMBL5907633 | 0.77 | ALDH1A1 (0.41) | HSD17B10ALDH1A1CYP2C9CYP2C19NT5E | |
| SCHEMBL30901433 | 0.75 | AURKA (0.53) | HSD17B10ALDH1A1CASP6CYP2C9CYP2C19 | |
| SCHEMBL229199 | 0.75 | AURKA (0.53) | HSD17B10ALDH1A1CASP6CYP2C9CYP2C19 | |
| SCHEMBL8379561 | 0.74 | AURKA (0.51) | HSD17B10ALDH1A1CASP6CYP2C9CYP2C19 | |
| SCHEMBL26983155 | 0.74 | AURKA (0.51) | HSD17B10ALDH1A1CASP6CYP2C9CYP2C19 | |
| SCHEMBL156092 | 0.73 | AURKA (0.62) | HSD17B10ALDH1A1CASP6CYP2C9CYP2C19 | |
| SCHEMBL29706553 | 0.73 | AURKA (0.62) | HSD17B10ALDH1A1CASP6CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090098076-A1 | Method For the Production of a Keratin-Binding Effector Molecule | BASF SE (DE) | 2009-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090098076-A1 | Method For the Production of a Keratin-Binding Effector Molecule | KRT18, KRTCAP2, CUTA | HSD17B10 2903/4885ALDH1A1 3750/4885CASP6 1371/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.