Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.56 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.52 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | NAMPT | P43490 | 1/20 | 0.48 |
| ▸ | MGLL | Q99685 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7278900 | 0.85 | ACHE (0.56) | ACHEEPHX1L3MBTL3L3MBTL1MEN1 | |
| SCHEMBL4678438 | 0.84 | ACHE (0.63) | ACHEEPHX1L3MBTL3L3MBTL1MEN1 | |
| SCHEMBL2781381 | 0.83 | MEN1 (0.68) | ACHEEPHX1L3MBTL3L3MBTL1MEN1 | |
| SCHEMBL7809522 | 0.82 | ACHE (0.64) | ACHEEPHX1L3MBTL3L3MBTL1MEN1 | |
| SCHEMBL4677007 | 0.82 | ACHE (0.59) | ACHEEPHX1L3MBTL3L3MBTL1MEN1 | |
| SCHEMBL27297520 | 0.81 | KCNA5 (0.57) | ACHEEPHX1MEN1KMT2AHPGD | |
| SCHEMBL27748883 | 0.78 | ACHE (0.68) | ACHEEPHX1L3MBTL3L3MBTL1MEN1 | |
| SCHEMBL28861303 | 0.78 | ACHE (0.62) | ACHEEPHX1L3MBTL3L3MBTL1MEN1 | |
| SCHEMBL4156411 | 0.78 | ACHE (0.58) | ACHEEPHX1L3MBTL3L3MBTL1MEN1 | |
| SCHEMBL14597201 | 0.77 | ACHE (0.61) | ACHEEPHX1L3MBTL3L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009072643-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-06-11 | — | — | WO | disclosed |