Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 9/20 | 0.51 |
| ▸ | TPSD1 | Q9BZJ3 | 9/20 | 0.51 |
| ▸ | TPSG1 | Q9NRR2 | 9/20 | 0.51 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22018450 | 0.87 | CYP1A2 (0.46) | TPSAB1TPSD1TPSG1CYP1A2TDP1 | |
| SCHEMBL17479229 | 0.85 | TPSAB1 (0.52) | TPSAB1TPSD1TPSG1KDM1A | |
| SCHEMBL22018451 | 0.84 | TPSAB1 (0.50) | TPSAB1TPSD1TPSG1HTT | |
| SCHEMBL21428432 | 0.84 | LMNA (0.47) | TPSAB1TPSD1TPSG1CYP1A2TDP1 | |
| SCHEMBL26124912 | 0.84 | TPSAB1 (0.55) | TPSAB1TPSD1TPSG1KDM1A | |
| SCHEMBL28067576 | 0.84 | TPSAB1 (0.55) | TPSAB1TPSD1TPSG1KDM1A | |
| SCHEMBL25565794 | 0.83 | TPSAB1 (0.48) | TPSAB1TPSD1TPSG1KDM1AHRH3 | |
| SCHEMBL21428419 | 0.82 | LMNA (0.50) | TPSAB1TPSD1TPSG1CYP1A2TDP1 | |
| SCHEMBL18505956 | 0.82 | CYP1A2 (0.42) | TPSAB1TPSD1TPSG1CYP1A2TDP1 | |
| SCHEMBL14852704 | 0.82 | HRH3 (0.56) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023083194-A1 | WEE1 PROTEIN KINASE DEGRADATION AGENT AND USE THEREOF | 杭州格博生物医药有限公司 | 2023-05-19 | — | — | WO | disclosed |
| WO-2009131246-A1 | SORDARIN DERIVATIVES FOR PREVENTING OR TREATING INFECTIOUS DISEASES CAUSED BY PATHOGENIC MICROORGANISMS | ASTELLAS PHARMA INC. (JP) | 2009-10-29 | — | — | WO | disclosed |
| WO-2009131246-A1 | SORDARIN DERIVATIVES FOR PREVENTING OR TREATING INFECTIOUS DISEASES CAUSED BY PATHOGENIC MICROORGANISMS | ASTELLAS PHARMA INC. (JP) | 2009-10-29 | — | — | WO | disclosed |