Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TPSAB1 | Q15661 | 6/20 | 0.42 |
| ▸ | TPSD1 | Q9BZJ3 | 6/20 | 0.42 |
| ▸ | TPSG1 | Q9NRR2 | 6/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SCN1A | P35498 | 1/20 | 0.41 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.41 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21428432 | 0.92 | LMNA (0.47) | CYP1A2TDP1HTTTPSAB1TPSD1 | |
| SCHEMBL22018451 | 0.92 | TPSAB1 (0.50) | HTTTPSAB1TPSD1TPSG1F2 | |
| SCHEMBL21428419 | 0.90 | LMNA (0.50) | CYP1A2TDP1HTTTPSAB1TPSD1 | |
| SCHEMBL15219283 | 0.87 | HTT (0.53) | HTTTPSAB1TPSD1TPSG1HRH3 | |
| SCHEMBL4283947 | 0.87 | TPSAB1 (0.51) | CYP1A2TDP1HTTTPSAB1TPSD1 | |
| SCHEMBL21739558 | 0.87 | HRH3 (0.45) | CYP1A2TDP1HTTTPSAB1TPSD1 | |
| SCHEMBL12820098 | 0.87 | TP53 (0.41) | CYP1A2TDP1HTTTPSAB1TPSD1 | |
| SCHEMBL18505956 | 0.82 | CYP1A2 (0.42) | CYP1A2TDP1HTTTPSAB1TPSD1 | |
| SCHEMBL19491339 | 0.82 | CYP1A2 (0.42) | CYP1A2TDP1HTTHRH3LMNA | |
| SCHEMBL25621683 | 0.81 | SCN1A (0.44) | HRH3MEN1KMT2ASCN1ASCN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024054469-A1 | ISOQUINOLONES AS PI3K INHIBITORS | ONKURE, INC. (US) | 2024-03-14 | — | — | WO | disclosed |
| US-20200157048-A1 | (2E,4E)-5-PHENYL-PENTA-2,4-DIEN-1-ONE DERIVATIVE | BIOWAY., INC (KR) | 2020-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200157048-A1 | (2E,4E)-5-PHENYL-PENTA-2,4-DIEN-1-ONE DERIVATIVE | PCK1, PCK2, ACACB | CYP1A2 3505/4885TDP1 4412/4885HTT 4563/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.