Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 18/20 | 0.50 |
| ▸ | TPSD1 | Q9BZJ3 | 18/20 | 0.50 |
| ▸ | TPSG1 | Q9NRR2 | 18/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.48 |
| ▸ | F2 | P00734 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21428432 | 0.96 | LMNA (0.47) | TPSAB1TPSD1TPSG1PRSS1F2 | |
| SCHEMBL21428419 | 0.94 | LMNA (0.50) | TPSAB1TPSD1TPSG1PRSS1F2 | |
| SCHEMBL22018450 | 0.92 | CYP1A2 (0.46) | TPSAB1TPSD1TPSG1PRSS1F2 | |
| SCHEMBL15219283 | 0.87 | HTT (0.53) | TPSAB1TPSD1TPSG1HTT | |
| SCHEMBL21739558 | 0.84 | HRH3 (0.45) | TPSAB1TPSD1TPSG1HTT | |
| SCHEMBL4283947 | 0.84 | TPSAB1 (0.51) | TPSAB1TPSD1TPSG1HTT | |
| SCHEMBL8275268 | 0.84 | TPSAB1 (0.51) | TPSAB1TPSD1TPSG1PRSS1F2 | |
| SCHEMBL28206534 | 0.82 | HSD11B1 (0.52) | TPSAB1TPSD1TPSG1PRSS1F2 | |
| SCHEMBL12153397 | 0.81 | TPSAB1 (0.49) | TPSAB1TPSD1TPSG1PRSS1F2 | |
| SCHEMBL7421428 | 0.80 | HPGD (0.54) | TPSAB1TPSD1TPSG1PRSS1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3778571-A1 | (2E,4E)-5-PHENYL-PENTA-2,4-DIEN-1-ONE DERIVATIVE | Bioway, Inc. (KR) | 2021-02-17 | — | — | EP | disclosed |
| US-20200157048-A1 | (2E,4E)-5-PHENYL-PENTA-2,4-DIEN-1-ONE DERIVATIVE | BIOWAY., INC (KR) | 2020-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200157048-A1 | (2E,4E)-5-PHENYL-PENTA-2,4-DIEN-1-ONE DERIVATIVE | PCK1, PCK2, ACACB | TPSAB1 1732/4885TPSD1 1442/4885TPSG1 2102/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.