Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 12/20 | 0.52 |
| ▸ | TUBB | P07437 | 12/20 | 0.52 |
| ▸ | TUBA3C | P0DPH7 | 12/20 | 0.52 |
| ▸ | TUBA1B | P68363 | 12/20 | 0.52 |
| ▸ | TUBA4A | P68366 | 12/20 | 0.52 |
| ▸ | TUBB4B | P68371 | 12/20 | 0.52 |
| ▸ | TUBB3 | Q13509 | 12/20 | 0.52 |
| ▸ | TUBB2A | Q13885 | 12/20 | 0.52 |
| ▸ | TUBB8 | Q3ZCM7 | 12/20 | 0.52 |
| ▸ | TUBA3E | Q6PEY2 | 12/20 | 0.52 |
| ▸ | TUBA1A | Q71U36 | 12/20 | 0.52 |
| ▸ | TUBA1C | Q9BQE3 | 12/20 | 0.52 |
| ▸ | TUBB6 | Q9BUF5 | 12/20 | 0.52 |
| ▸ | TUBB2B | Q9BVA1 | 12/20 | 0.52 |
| ▸ | TUBB1 | Q9H4B7 | 12/20 | 0.52 |
| ▸ | ACLY | P53396 | 4/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10176544 | 0.91 | ACLY (0.48) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL429228 | 0.90 | TUBB4A (0.56) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL424297 | 0.84 | TUBB4A (0.53) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL429321 | 0.83 | ACLY (0.46) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL10176354 | 0.81 | CA12 (0.47) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL424094 | 0.81 | PDE4A (0.50) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL428130 | 0.79 | ACLY (0.54) | ACLYCA12CA2CA9HDAC1 | |
| SCHEMBL426732 | 0.78 | CA12 (0.49) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL3558271 | 0.77 | ACLY (0.67) | ACLYCA12CA2CA9 | |
| SCHEMBL10176560 | 0.77 | ACLY (0.46) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120022121-A1 | INDOLES, DERIVATIVES AND ANALOGS THEREOF AND USES THEREFOR | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2012-01-26 | — | — | US | disclosed |
| US-20120022121-A1 | INDOLES, DERIVATIVES AND ANALOGS THEREOF AND USES THEREFOR | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2012-01-26 | — | — | US | disclosed |
| US-20120022121-A1 | INDOLES, DERIVATIVES AND ANALOGS THEREOF AND USES THEREFOR | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2012-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120022121-A1 | INDOLES, DERIVATIVES AND ANALOGS THEREOF AND USES THEREFOR | TUBB, TUBB3, TUBB1 | TUBB4A 6/4885TUBB 1/4885TUBA3C 24/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.