Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SCN1A | P35498 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL791912 | 0.87 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2KEAP1KDM4ELMNA | |
| SCHEMBL684590 | 0.82 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2KEAP1KDM4ELMNA | |
| SCHEMBL14300251 | 0.80 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2KEAP1KDM4ELMNA | |
| SCHEMBL792222 | 0.80 | SIGMAR1 (0.45) | ALDH1A1SMN1; SMN2KEAP1KDM4EGLA | |
| SCHEMBL24065992 | 0.80 | CA12 (0.44) | ALDH1A1SMN1; SMN2KEAP1KDM4ELMNA | |
| SCHEMBL425365 | 0.79 | SIGMAR1 (0.47) | SIGMAR1CYP1A2HRH3 | |
| SCHEMBL8896209 | 0.79 | USP2 (0.35) | ALDH1A1SMN1; SMN2KEAP1KDM4EGLA | |
| SCHEMBL154374 | 0.79 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2KEAP1KDM4EGLA | |
| SCHEMBL2733378 | 0.78 | KEAP1 (0.53) | ALDH1A1SMN1; SMN2KEAP1KDM4ELMNA | |
| SCHEMBL18024043 | 0.78 | CHRM3 (0.40) | ALDH1A1SMN1; SMN2KEAP1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117417265-A | Lipid composition | 富士胶片株式会社 | 2024-01-19 | — | — | CN | disclosed |
| CN-112262122-B | Compound or salt and lipid particle thereof | 富士胶片株式会社 | 2023-10-13 | — | — | CN | disclosed |
| CN-116172975-A | Lipid particle, nucleic acid drug comprising same, and composition for nucleic acid delivery | 富士胶片株式会社 | 2023-05-30 | — | — | CN | disclosed |
| CN-114728016-A | Lipid composition | 富士胶片株式会社 | 2022-07-08 | — | — | CN | disclosed |
| CN-113924128-A | Lipid composition | 富士胶片株式会社 | 2022-01-11 | — | — | CN | disclosed |
| CN-112262122-A | Compound or salt thereof, and lipid particle | 富士胶片株式会社 | 2021-01-22 | — | — | CN | disclosed |
| US-20120020920-A1 | 5-5-MEMBERED FUSED HETEROCYCLIC COMPOUND AND USE THEREOF AS HCV POLYMERASE INHIBITOR | JAPAN TOBACCO INC. (JP) | 2012-01-26 | — | — | US | disclosed |
| US-20090036444-A1 | 5-5-Membered fused heterocyclic compound and use thereof as HCV polymerase inhibitor | JAPAN TOBACCO INC. (JP) | 2009-02-05 | — | — | US | disclosed |
| EP-1688420-A1 | 5-5-MEMBERED FUSED HETEROCYCLIC COMPOUND AND USE THEREOF AS HCV POLYMERASE INHIBITOR | JAPAN TOBACCO INC. (JP) | 2006-08-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090036444-A1 | 5-5-Membered fused heterocyclic compound and use thereof as HCV polymerase inhibitor | GTF3C5, ZC3HAV1, POLI | ALDH1A1 596/4885SMN1; SMN2 4383/4885KEAP1 408/4885 |
| US-20120020920-A1 | 5-5-MEMBERED FUSED HETEROCYCLIC COMPOUND AND USE THEREOF AS HCV POLYMERASE INHIBITOR | GTF3C5, ZC3HAV1, POLI | ALDH1A1 596/4885SMN1; SMN2 4383/4885KEAP1 408/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.