Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.41 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.41 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4281912 | 0.88 | KMT2A (0.50) | ALDH1A1HPGDHSD17B10L3MBTL1NPC1 | |
| SCHEMBL4284676 | 0.87 | MAPT (0.43) | ALDH1A1POLBCYP2C19HPGDHSD17B10 | |
| SCHEMBL4285755 | 0.86 | KDM4E (0.51) | ALDH1A1POLBCYP2C19HPGDL3MBTL1 | |
| SCHEMBL4284544 | 0.85 | ALDH1A1 (0.45) | ALDH1A1POLBCYP2C19LMNAKMT2A | |
| SCHEMBL4287265 | 0.83 | KDM4E (0.45) | ALDH1A1HPGDHSD17B10LMNAKMT2A | |
| SCHEMBL4289383 | 0.83 | RAB9A (0.43) | ALDH1A1CYP2C19HPGDSMN1; SMN2NPC1 | |
| SCHEMBL4294041 | 0.83 | HCRTR1 (0.40) | ALDH1A1POLBHPGDHSD17B10KMT2A | |
| SCHEMBL4287638 | 0.81 | LMNA (0.50) | ALDH1A1POLBHPGDL3MBTL1SMN1; SMN2 | |
| SCHEMBL4291256 | 0.81 | PPARD (0.45) | ALDH1A1HPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL4291908 | 0.81 | HPGD (0.44) | ALDH1A1POLBCYP2C19HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090156612-A1 | Substituted imidazole compound and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156612-A1 | Substituted imidazole compound and use thereof | REN, ACE, AGT | ALDH1A1 388/4885POLB 3799/4885CYP2C19 19/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.