SCHEMBL4285318

SCHEMBL4285318

CCc1ccc(C(OC(C)=O)c2ccc(C)nc2)c(OCc2ccccc2)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXRA P19793 2/20 0.38
FFAR1 O14842 1/20 0.38
FFAR4 Q5NUL3 1/20 0.37
ALDH1A1 P00352 1/20 0.37
MAPT P10636 2/20 0.36
POLB P06746 1/20 0.36
THRB P10828 1/20 0.36
CYP11B1 P15538 1/20 0.36
CYP11B2 P19099 1/20 0.36
MRGPRX4 Q96LA9 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
MTNR1A P48039 1/20 0.35
MTNR1B P49286 1/20 0.35
APP P05067 1/20 0.35
LRRK2 Q5S007 1/20 0.35
KEAP1 Q14145 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4289338 0.87 LRRK2 (0.43) RXRAFFAR1MAPTPOLBMRGPRX4
SCHEMBL4285312 0.78 CNR2 (0.37) RXRAFFAR1ALDH1A1MAPTL3MBTL1
SCHEMBL4282622 0.74 L3MBTL1 (0.47) RXRAFFAR1ALDH1A1MAPTPOLB
SCHEMBL5377826 0.73 FFAR4 (0.39) RXRAFFAR4MAPTPOLBTHRB
SCHEMBL154397 0.70 GAA (0.46) ALDH1A1POLBCYP11B1CYP11B2SMN1; SMN2
SCHEMBL4289336 0.69 CNR2 (0.42) FFAR1ALDH1A1LMNA
SCHEMBL7283906 0.69 MEN1 (0.48) FFAR1MAPTPOLBL3MBTL1KDM4E
SCHEMBL18066348 0.68 MAOB (0.61) MAPTCYP2C9CYP2C19SMN1; SMN2TDP1
SCHEMBL28085736 0.66 ALOX15 (0.54) FFAR1FFAR4MAPTPOLBTHRB
SCHEMBL6243360 0.66 ALDH1A1 (0.53) FFAR4ALDH1A1MAPTCYP11B1CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090137499-A1 BENZYLPHENYL GLUCOPYRANOSIDE DERIVATIVE DAIICHI SANKYO COMPANY, LIMITED (JP) 2009-05-28 US disclosed
EP-2048150-A1 BENZYL PHENYL GLUCOPYRANOSIDE DERIVATIVE Daiichi Sankyo Company, Limited (JP) 2009-04-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090137499-A1 BENZYLPHENYL GLUCOPYRANOSIDE DERIVATIVE SLC5A1, SLC5A2, SLC2A1 RXRA 2352/4885FFAR1 333/4885FFAR4 470/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.